PMID- 25488377 OWN - NLM STAT- MEDLINE DCOM- 20150804 LR - 20181202 IS - 1872-8227 (Electronic) IS - 0168-8227 (Linking) VI - 107 IP - 1 DP - 2015 Jan TI - A meta-analysis of passive smoking and risk of developing Type 2 Diabetes Mellitus. PG - 9-14 LID - S0168-8227(14)00419-7 [pii] LID - 10.1016/j.diabres.2014.09.019 [doi] AB - AIMS: To assess passive smoking as a risk factor for developing type 2 Diabetes Mellitus (T2DM). METHODS: A search of PubMed, Web of Knowledge, Elsevier ScienceDirect and Springer (up to March, 2014) databases were performed using subject and random words. Two authors independently extracted the data. The Newcastle-Ottawa Scale (NOS) was used to assess the quality of included studies. The odds ratio (ORs) for the association was determined using a fix-effects model. Subgroup and sensitivity analyses were performed and publication bias was assessed. RESULT: 7 prospective studies were included in this meta-analysis which included a total of 162,001 subjects. The overall OR for developing T2DM for passive smoking was 1.33 (95% confidence interval (CI) 1.20-1.46), with no significant heterogeneity between studies. The result was stable in the subgroup and sensitivity analyses, however there was evidence of publication bias. After the "fill and trim" method, the recalculated OR was 1.27 (95%CI 1.16-1.40). CONCLUSIONS: Passive smoking is a risk factor of T2DM even in those who were not themselves active smokers. CI - Copyright (c) 2014 Elsevier Ireland Ltd. All rights reserved. FAU - Wei, Xiaomin AU - Wei X AD - Institute of Occupational Health and Environmental, Health, Shandong University, 44 Wenhua Xi Road, Jinan, 250012 Shandong, PR China. FAU - E, Meng AU - E M AD - Institute of Occupational Health and Environmental, Health, Shandong University, 44 Wenhua Xi Road, Jinan, 250012 Shandong, PR China. FAU - Yu, Sufang AU - Yu S AD - Institute of Occupational Health and Environmental, Health, Shandong University, 44 Wenhua Xi Road, Jinan, 250012 Shandong, PR China. Electronic address: sufangyu@sdu.edu.cn. LA - eng PT - Journal Article PT - Meta-Analysis PT - Review DEP - 20141014 PL - Ireland TA - Diabetes Res Clin Pract JT - Diabetes research and clinical practice JID - 8508335 RN - 0 (Tobacco Smoke Pollution) SB - IM MH - Diabetes Mellitus, Type 2/*epidemiology/etiology MH - Humans MH - Odds Ratio MH - Prospective Studies MH - Risk Factors MH - Tobacco Smoke Pollution/adverse effects/*statistics & numerical data OTO - NOTNLM OT - Meta-analysis OT - OR OT - Passive smoking OT - Publication bias OT - T2DM EDAT- 2014/12/10 06:00 MHDA- 2015/08/05 06:00 CRDT- 2014/12/10 06:00 PHST- 2014/04/08 00:00 [received] PHST- 2014/05/25 00:00 [revised] PHST- 2014/09/14 00:00 [accepted] PHST- 2014/12/10 06:00 [entrez] PHST- 2014/12/10 06:00 [pubmed] PHST- 2015/08/05 06:00 [medline] AID - S0168-8227(14)00419-7 [pii] AID - 10.1016/j.diabres.2014.09.019 [doi] PST - ppublish SO - Diabetes Res Clin Pract. 2015 Jan;107(1):9-14. doi: 10.1016/j.diabres.2014.09.019. Epub 2014 Oct 14.