PMID- 25489302
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20141209
LR  - 20200930
IS  - 1734-9338 (Print)
IS  - 1897-4295 (Electronic)
IS  - 1734-9338 (Linking)
VI  - 10
IP  - 3
DP  - 2014
TI  - Long-term prognostic value of admission haemoglobin A1c (HbA1c) levels in 
      patients with ST-segment elevation myocardial infarction undergoing primary 
      percutaneous coronary intervention.
PG  - 166-74
LID - 10.5114/pwki.2014.45143 [doi]
AB  - INTRODUCTION: Many studies have reported the diagnostic and prognostic value of 
      haemoglobin A1c (HbA1c) levels in patients with acute coronary syndrome. However, 
      the short- and long-term prognostic value of HbA1c level in patients with ST 
      elevation myocardial infarction (STEMI) undergoing percutaneous coronary 
      intervention (PCI) is controversial. AIM: To investigate whether admission HbA1c 
      level has a prognostic value for in-hospital, short-, and long-term 
      cardiovascular (CV) mortality and major adverse cardiovascular events in patients 
      with STEMI undergoing primary PCI. MATERIAL AND METHODS: This prospective study 
      included 443 consecutive patients with STEMI who underwent primary PCI between 
      September 2010 and July 2012. The patients were divided into three groups based 
      on admission HbA1c levels: group I (HbA1c </= 5.6%), group II (HbA1c 5.7-6.4%), and 
      group III (HbA1c >/= 6.5%). The in-hospital, 1-month, and 1-year CV events of all 3 
      patient groups were followed up. RESULTS: A significant association was found 
      between HbA1c level and 1-year primary clinical outcomes, including CV mortality, 
      non-fatal reinfarction, and stroke (p = 0.037). In addition, age, Killip class > 
      1, and left ventricular ejection fraction were found to be independent predictors 
      of long-term CV mortality in multivariate analysis (hazard ratios (95% confidence 
      interval) 1.081 (1.020-1.146), 4.182 (1.171-14.935), and 0.832 (0.752-0.920); p = 
      0.009, p = 0.028, and p < 0.001, respectively). CONCLUSIONS: In this study, we 
      demonstrated that increased admission HbA1c levels were associated with higher 
      rates of major adverse CV events, including mortality, non-fatal reinfarction, 
      and stroke, in patients with STEMI who underwent primary PCI.
FAU - Pusuroglu, Hamdi
AU  - Pusuroglu H
AD  - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Istanbul, Turkey.
FAU - Akgul, Ozgur
AU  - Akgul O
AD  - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Istanbul, Turkey.
FAU - Cakmak, Huseyin Altug
AU  - Cakmak HA
AD  - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Istanbul, Turkey.
FAU - Erturk, Mehmet
AU  - Erturk M
AD  - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Istanbul, Turkey.
FAU - Surgit, Ozgur
AU  - Surgit O
AD  - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Istanbul, Turkey.
FAU - Celik, Omer
AU  - Celik O
AD  - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Istanbul, Turkey.
FAU - Ozturk, Derya
AU  - Ozturk D
AD  - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Istanbul, Turkey.
FAU - Uzun, Fatih
AU  - Uzun F
AD  - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Istanbul, Turkey.
FAU - Akkaya, Emre
AU  - Akkaya E
AD  - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Istanbul, Turkey.
FAU - Yildirim, Aydin
AU  - Yildirim A
AD  - Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery 
      Training and Research Hospital, Istanbul, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20140911
PL  - Poland
TA  - Postepy Kardiol Interwencyjnej
JT  - Postepy w kardiologii interwencyjnej = Advances in interventional cardiology
JID - 101272671
PMC - PMC4252307
OTO - NOTNLM
OT  - ST-segment elevation myocardial infarction
OT  - haemoglobin A1c
OT  - primary percutaneous coronary intervention
OT  - prognosis
EDAT- 2014/12/10 06:00
MHDA- 2014/12/10 06:01
PMCR- 2014/01/01
CRDT- 2014/12/10 06:00
PHST- 2014/01/30 00:00 [received]
PHST- 2014/03/17 00:00 [revised]
PHST- 2014/04/28 00:00 [accepted]
PHST- 2014/12/10 06:00 [entrez]
PHST- 2014/12/10 06:00 [pubmed]
PHST- 2014/12/10 06:01 [medline]
PHST- 2014/01/01 00:00 [pmc-release]
AID - 23508 [pii]
AID - 10.5114/pwki.2014.45143 [doi]
PST - ppublish
SO  - Postepy Kardiol Interwencyjnej. 2014;10(3):166-74. doi: 10.5114/pwki.2014.45143. 
      Epub 2014 Sep 11.