PMID- 25492671
OWN - NLM
STAT- MEDLINE
DCOM- 20150827
LR  - 20181202
IS  - 0301-0430 (Print)
IS  - 0301-0430 (Linking)
VI  - 83
IP  - 6
DP  - 2015 Jun
TI  - Light chain deposition disease and proximal tubulopathy in two successive kidney 
      allografts.
PG  - 351-6
LID - 10.5414/CN108319 [doi]
AB  - Light chain proximal tubulopathy (LCPT) is a rare kidney disease associated with 
      plasma cell dyscrasias, characterized by light chain deposits in the proximal 
      tubular cells, with or without crystal formation. We describe an exceptional case 
      of LCPT without crystal formation in a kidney allograft, in a patient who 
      underwent two renal transplants for a light chain deposition disease (LCDD) 
      complicating smoldering myeloma. This is the first description of this 
      association in successive kidney allografts. We concisely describe pathology of 
      LCDD and LCPT and discuss potential pathophysiological mechanisms relating these 
      two conditions.
FAU - Drieux, Fanny
AU  - Drieux F
FAU - Loron, Marie-Charlotte
AU  - Loron MC
FAU - Francois, Arnaud
AU  - Francois A
FAU - Bertrand, Dominique
AU  - Bertrand D
FAU - Etienne, Isabelle
AU  - Etienne I
FAU - Bender, Sebastien
AU  - Bender S
FAU - Godin, Michel
AU  - Godin M
FAU - Guerrot, Dominique
AU  - Guerrot D
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Germany
TA  - Clin Nephrol
JT  - Clinical nephrology
JID - 0364441
RN  - 0 (Immunoglobulin Light Chains)
SB  - IM
MH  - Adult
MH  - Allografts
MH  - Humans
MH  - Immunoglobulin Light Chains/*metabolism
MH  - Kidney/pathology
MH  - Kidney Diseases/*surgery
MH  - *Kidney Transplantation
MH  - Kidney Tubules, Proximal/*metabolism
MH  - Male
MH  - Paraproteinemias/*complications
EDAT- 2014/12/11 06:00
MHDA- 2015/08/28 06:00
CRDT- 2014/12/11 06:00
PHST- 2015/05/22 00:00 [accepted]
PHST- 2014/12/11 06:00 [entrez]
PHST- 2014/12/11 06:00 [pubmed]
PHST- 2015/08/28 06:00 [medline]
AID - 12865 [pii]
AID - 10.5414/CN108319 [doi]
PST - ppublish
SO  - Clin Nephrol. 2015 Jun;83(6):351-6. doi: 10.5414/CN108319.