PMID- 25493502
OWN - NLM
STAT- MEDLINE
DCOM- 20191028
LR  - 20191028
IS  - 1526-9914 (Electronic)
IS  - 1526-9914 (Linking)
VI  - 15
IP  - 6
DP  - 2014 Sep 8
TI  - The optimization of superficial planning target volumes (PTVs) with helical 
      tomotherapy.
PG  - 4560
LID - 10.1120/jacmp.v15i6.4560 [doi]
AB  - When the planning target volume (PTV), extends close to or beyond the skin, 
      inverse-planned intensity-modulated radiotherapy can boost the fluence from tan- 
      gential angles to superficial parts of the PTV due to the buildup effect. This 
      can result in significant regions of high dose upon a small movement in the 
      patient's position. We analyzed different methods of reducing this effect in the 
      TomoTherapy planning system, including using pretend bolus, clipping the PTV back 
      from the skin surface, and combinations of both. No alternative technique was 
      seen to be unconditionally superior to a 5 mm planning bolus. A clip distance of 
      3 mm gave acceptable results, but consideration should be given to the reduction 
      in minimum dose or increase in maximum dose seen in clip distances just 1 mm less 
      or more, respectively, when treating head and neck cases in TomoTherapy. 
FAU - Ashburner, Mark J
AU  - Ashburner MJ
AD  - Addenbrooke's Hospital Cambridge. mark.ashburner@waikatodhb.health.nz.
FAU - Tudor, Samuel
AU  - Tudor S
LA  - eng
PT  - Journal Article
DEP - 20140908
PL  - United States
TA  - J Appl Clin Med Phys
JT  - Journal of applied clinical medical physics
JID - 101089176
SB  - IM
EIN - J Appl Clin Med Phys. 2017 Jul;18(4):237. PMID: 28681450
MH  - Humans
MH  - Phantoms, Imaging
MH  - Radiotherapy Dosage
MH  - *Radiotherapy Planning, Computer-Assisted/methods
MH  - *Radiotherapy, Intensity-Modulated/methods
PMC - PMC5711130
EDAT- 2014/12/11 06:00
MHDA- 2014/12/11 06:01
PMCR- 2014/09/08
CRDT- 2014/12/11 06:00
PHST- 2013/05/30 00:00 [received]
PHST- 2014/08/11 00:00 [accepted]
PHST- 2014/08/26 00:00 [revised]
PHST- 2014/12/11 06:00 [entrez]
PHST- 2014/12/11 06:00 [pubmed]
PHST- 2014/12/11 06:01 [medline]
PHST- 2014/09/08 00:00 [pmc-release]
AID - ACM20004 [pii]
AID - 10.1120/jacmp.v15i6.4560 [doi]
PST - epublish
SO  - J Appl Clin Med Phys. 2014 Sep 8;15(6):4560. doi: 10.1120/jacmp.v15i6.4560.