PMID- 25504136
OWN - NLM
STAT- MEDLINE
DCOM- 20160301
LR  - 20171116
IS  - 2042-650X (Electronic)
IS  - 2042-6496 (Linking)
VI  - 6
IP  - 2
DP  - 2015 Feb
TI  - In vitro assessment of the prebiotic potential of Aloe vera mucilage and its 
      impact on the human microbiota.
PG  - 525-31
LID - 10.1039/c4fo00857j [doi]
AB  - Aloe vera mucilage is reported to be rich in acemannan that is a polysaccharide 
      with a backbone of beta-(1-->4)-D-mannose residues acetylated at the C-2 and C-3 
      positions and contains some side chains of galactose and arabinose attached to 
      the C-6 carbon. The evaluation of the prebiotic potential of Aloe vera mucilage 
      was carried out by in vitro fermentation using intestinal microbiota from six 
      healthy donors as the inoculum. The prebiotic activity was assessed through the 
      quantification of short chain fatty acids (SCFA) and the evaluation of dynamic 
      bacterial population in mixed faecal cultures by fluorescence in situ 
      hybridization (FISH). Our findings support the possible incorporation of the Aloe 
      vera mucilage in the development of a variety of food products known as 
      prebiotics aimed at improving gastrointestinal health.
FAU - Gullon, Beatriz
AU  - Gullon B
AD  - Centro de Biotecnologia e Quimica Fina - Laboratorio Associado, Escola Superior 
      de Biotecnologia, Universidade Catolica Portuguesa, Rua Doutor Antonio Bernardino 
      de Almeida, 4200-72, Porto, Portugal. mpintado@porto.ucp.pt.
FAU - Gullon, Patricia
AU  - Gullon P
FAU - Tavaria, Freni
AU  - Tavaria F
FAU - Alonso, Jose Luis
AU  - Alonso JL
FAU - Pintado, Manuela
AU  - Pintado M
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - Food Funct
JT  - Food & function
JID - 101549033
RN  - 0 (Culture Media)
RN  - 0 (Fatty Acids, Volatile)
RN  - 0 (Mannans)
RN  - 0 (Plant Mucilage)
RN  - 0 (Prebiotics)
RN  - B40ROO395Z (Arabinose)
RN  - PHA4727WTP (Mannose)
RN  - UZ29E6L2X8 (acemannan)
RN  - X2RN3Q8DNE (Galactose)
SB  - IM
MH  - Adult
MH  - Aloe/*chemistry
MH  - Arabinose/chemistry
MH  - Culture Media
MH  - Fatty Acids, Volatile/analysis
MH  - Feces/chemistry/microbiology
MH  - Female
MH  - Fermentation
MH  - Galactose/chemistry
MH  - Gastrointestinal Microbiome/*drug effects
MH  - Gastrointestinal Tract/drug effects/metabolism/microbiology
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Male
MH  - Mannans/analysis/pharmacology
MH  - Mannose/chemistry
MH  - Plant Mucilage/chemistry/*pharmacology
MH  - Prebiotics/*analysis
EDAT- 2014/12/17 06:00
MHDA- 2016/03/02 06:00
CRDT- 2014/12/16 06:00
PHST- 2014/12/16 06:00 [entrez]
PHST- 2014/12/17 06:00 [pubmed]
PHST- 2016/03/02 06:00 [medline]
AID - 10.1039/c4fo00857j [doi]
PST - ppublish
SO  - Food Funct. 2015 Feb;6(2):525-31. doi: 10.1039/c4fo00857j.