PMID- 25504281
OWN - NLM
STAT- MEDLINE
DCOM- 20150824
LR  - 20171221
IS  - 1526-2359 (Electronic)
IS  - 1073-2748 (Linking)
VI  - 22
IP  - 1
DP  - 2015 Jan
TI  - Using HLA typing to support patients with cancer.
PG  - 79-86
AB  - BACKGROUND: The human leukocyte antigen (HLA) system plays a crucial role in 
      immune function, and HLA testing is often needed in the support of patients with 
      cancer. METHODS: We briefly review the published literature to clarify the 
      nomenclature of the HLA system, currently available methods for HLA testing, and 
      commonly used HLA assays. The uses of HLA testing in pharmacogenomics, disease 
      association, platelet transfusion support, and in the management of both solid 
      organ and hematopoietic stem cell transplantation are also reviewed. RESULTS: HLA 
      testing is commonly performed for select patient populations, including patients 
      with cancer and in those requiring solid organ and hematopoietic stem cell 
      transplantation. CONCLUSION: Newer molecular typing methods have helped improve 
      patient outcomes following hematopoietic stem cell transplantation.
FAU - Fung, Mark K
AU  - Fung MK
AD  - Department of Pathology, Blood Bank and HLA Laboratory, University of Vermont 
      Medical Center, Burlington, 05401, USA. Mark.Fung@vtmednet.org.
FAU - Benson, Kaaron
AU  - Benson K
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Cancer Control
JT  - Cancer control : journal of the Moffitt Cancer Center
JID - 9438457
RN  - 0 (HLA Antigens)
SB  - IM
MH  - HLA Antigens/*classification/*genetics
MH  - Hematopoietic Stem Cell Transplantation
MH  - Histocompatibility Testing/*methods
MH  - Humans
MH  - Neoplasms/*therapy
MH  - Organ Transplantation
MH  - Platelet Transfusion
EDAT- 2014/12/17 06:00
MHDA- 2015/08/25 06:00
CRDT- 2014/12/16 06:00
PHST- 2014/12/16 06:00 [entrez]
PHST- 2014/12/17 06:00 [pubmed]
PHST- 2015/08/25 06:00 [medline]
AID - 10.1177/107327481502200110 [doi]
PST - ppublish
SO  - Cancer Control. 2015 Jan;22(1):79-86. doi: 10.1177/107327481502200110.