PMID- 25510880
OWN - NLM
STAT- MEDLINE
DCOM- 20160105
LR  - 20191210
IS  - 1878-4216 (Electronic)
IS  - 0278-5846 (Linking)
VI  - 58
DP  - 2015 Apr 3
TI  - Interactions between specific parameters of MDMA use and cognitive and 
      psychopathological measures.
PG  - 32-7
LID - S0278-5846(14)00241-3 [pii]
LID - 10.1016/j.pnpbp.2014.12.004 [doi]
AB  - The aim of the present study was to investigate the relevance of different 
      parameters of 3,4-methylenedioxymethamphetamine (MDMA) use, including age of 
      first use, cumulative lifetime dose and highest daily dose for predicting 
      cognitive performance and self-reported psychopathology. Moreover, interactions 
      between those parameters were examined. Ninety-six new MDMA users were 
      interviewed to assess their drug use, and they completed a battery of cognitive 
      tests concerning attention and information processing speed, episodic memory and 
      executive functioning and self-reported psychopathology. Subjects participated 
      again after 1year to provide follow-up data. Significant associations between age 
      of first use and cumulative lifetime dose have been found for attention and 
      information processing speed. Furthermore, the results showed a significant 
      effect of age of first use on the recognition performance of the episodic memory. 
      The findings of the current study provide a first estimation of the interactions 
      between different MDMA use parameters. Future research should focus upon 
      additional parameters of drug use and concentrate on consequent follow-up 
      effects.
CI  - Copyright (c) 2014 Elsevier Inc. All rights reserved.
FAU - Wagner, Daniel
AU  - Wagner D
AD  - Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener 
      Strasse 62, Cologne 50924, Germany.
FAU - Adolph, Sophia
AU  - Adolph S
AD  - Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener 
      Strasse 62, Cologne 50924, Germany.
FAU - Koester, Philip
AU  - Koester P
AD  - Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener 
      Strasse 62, Cologne 50924, Germany.
FAU - Becker, Benjamin
AU  - Becker B
AD  - Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener 
      Strasse 62, Cologne 50924, Germany.
FAU - Gouzoulis-Mayfrank, Euphrosyne
AU  - Gouzoulis-Mayfrank E
AD  - Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener 
      Strasse 62, Cologne 50924, Germany.
FAU - Daumann, Joerg
AU  - Daumann J
AD  - Department of Psychiatry and Psychotherapy, University of Cologne, Kerpener 
      Strasse 62, Cologne 50924, Germany. Electronic address: 
      joerg.daumann@uk-koeln.de.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20141213
PL  - England
TA  - Prog Neuropsychopharmacol Biol Psychiatry
JT  - Progress in neuro-psychopharmacology & biological psychiatry
JID - 8211617
RN  - 0 (Hallucinogens)
RN  - KE1SEN21RM (N-Methyl-3,4-methylenedioxyamphetamine)
SB  - IM
MH  - Adult
MH  - Age of Onset
MH  - Amphetamine-Related Disorders/complications/*psychology
MH  - Attention/drug effects
MH  - Cognition/*drug effects
MH  - Dose-Response Relationship, Drug
MH  - Educational Status
MH  - Executive Function/drug effects
MH  - Female
MH  - Follow-Up Studies
MH  - Hallucinogens/*administration & dosage
MH  - Humans
MH  - Male
MH  - Marijuana Abuse/complications/psychology
MH  - Memory, Episodic
MH  - N-Methyl-3,4-methylenedioxyamphetamine/*administration & dosage
MH  - Neuropsychological Tests
MH  - Recognition, Psychology/drug effects
MH  - Young Adult
OTO - NOTNLM
OT  - 3,4-Methylenedioxymethamphetamine
OT  - Attention
OT  - Information processing
OT  - MDMA
OT  - Memory
OT  - Neuropsychology
EDAT- 2014/12/17 06:00
MHDA- 2016/01/06 06:00
CRDT- 2014/12/17 06:00
PHST- 2014/09/11 00:00 [received]
PHST- 2014/11/25 00:00 [revised]
PHST- 2014/12/08 00:00 [accepted]
PHST- 2014/12/17 06:00 [entrez]
PHST- 2014/12/17 06:00 [pubmed]
PHST- 2016/01/06 06:00 [medline]
AID - S0278-5846(14)00241-3 [pii]
AID - 10.1016/j.pnpbp.2014.12.004 [doi]
PST - ppublish
SO  - Prog Neuropsychopharmacol Biol Psychiatry. 2015 Apr 3;58:32-7. doi: 
      10.1016/j.pnpbp.2014.12.004. Epub 2014 Dec 13.