PMID- 25511492 OWN - NLM STAT- MEDLINE DCOM- 20150901 LR - 20181202 IS - 0376-2491 (Print) IS - 0376-2491 (Linking) VI - 94 IP - 33 DP - 2014 Sep 9 TI - [Mortality risks of type 2 diabetes mellitus among elderly patients: a 17-year cohort study]. PG - 2597-601 AB - OBJECTIVE: To explore the mortality risks of elders with and without type 2 diabetes mellitus (T2DM) during a fellow-up period of 17 years. METHODS: The subjects were elderly patients (>60 years old) undergoing annual health examinations at our hospital. And the incidence and risk factors were analyzed by Kaplan-Meier method and COX's proportional hazard. RESULTS: A total of 2 142 subjects were divided into T2DM group (DM, n = 746) and non-T2DM group (N-DM, n = 1 396). During a 17-year follow-up, the mortality rate of all causes was 50.9% in DM group versus 32.45% in N-DM group (P < 0.01). The major mortality causes were malignant tumor, respiratory disease and cardiovascular disease. Kaplan-Meier analysis revealed that the accumulative mortality of all causes and cardiovascular with DM was significantly above that of N-DM. The independent mortality risk factors of elders was T2DM (P < 0.01, HR = 1.36, 95% CI: 1.192-1.558) and cardiovascular disease (P < 0.01, HR = 3.26, 95% CI: 2.887-3.690) based upon the COX's proportional hazard analysis. CONCLUSION: Type 2 diabetes mellitus is an independent risk factor for elders with increased mortality risk. FAU - Kan, Fangfang AU - Kan F AD - Department of Senile Endocrinology, PLA General Hospital, Beijing 100853, China. FAU - Fang, Fusheng AU - Fang F AD - Department of Senile Endocrinology, PLA General Hospital, Beijing 100853, China. FAU - Tian, Hui AU - Tian H AD - Department of Senile Endocrinology, PLA General Hospital, Beijing 100853, China. Email: tianhui@medmail.com.cn. FAU - Li, Chunlin AU - Li C AD - Department of Senile Endocrinology, PLA General Hospital, Beijing 100853, China. FAU - Liu, Minyan AU - Liu M AD - Department of Senile Endocrinology, PLA General Hospital, Beijing 100853, China. FAU - Lu, Yanhui AU - Lu Y AD - Department of Senile Endocrinology, PLA General Hospital, Beijing 100853, China. FAU - Sun, Banruo AU - Sun B AD - Department of Senile Endocrinology, PLA General Hospital, Beijing 100853, China. FAU - Wang, Chuanhai AU - Wang C AD - Department of Senile Endocrinology, PLA General Hospital, Beijing 100853, China. LA - chi PT - Journal Article PL - China TA - Zhonghua Yi Xue Za Zhi JT - Zhonghua yi xue za zhi JID - 7511141 SB - IM MH - Aged MH - Cardiovascular Diseases MH - Cohort Studies MH - *Diabetes Mellitus, Type 2 MH - Follow-Up Studies MH - Humans MH - Incidence MH - Kaplan-Meier Estimate MH - Proportional Hazards Models MH - Risk Factors EDAT- 2014/12/17 06:00 MHDA- 2015/09/02 06:00 CRDT- 2014/12/17 06:00 PHST- 2014/12/17 06:00 [entrez] PHST- 2014/12/17 06:00 [pubmed] PHST- 2015/09/02 06:00 [medline] PST - ppublish SO - Zhonghua Yi Xue Za Zhi. 2014 Sep 9;94(33):2597-601.