PMID- 25514504 OWN - NLM STAT- MEDLINE DCOM- 20151215 LR - 20161125 IS - 1361-6579 (Electronic) IS - 0967-3334 (Linking) VI - 36 IP - 1 DP - 2015 Jan TI - On the risk of aortic valve replacement surgery assessed by heart rate variability parameters. PG - 163-75 LID - 10.1088/0967-3334/36/1/163 [doi] AB - In recent years the number of arterial stenosis (AS) patients has grown rapidly and valvular disease is expected to be the next great epidemic. We studied a group of 385 arterial valve replacement (AVR) surgery patients, of whom 16 had died in the postoperational period (up to 30 d after the operation). Each patient had a heart rate variability (HRV) recording made prior to the operation in addition to a full set of medical diagnostics including echocardiography. We formed 16 age, sex, New York Heart Association (NYHA) class, and BMI adjusted control pairs for each person who died in the perioperative period. Our aim was to find indications of the risk from AVR surgery based on the medical data and HRV properties. Besides standard, linear HRV methods, we used indexes of time irreversibility introduced by Guzik (G%), Porta (P%), Ehlers (index E) and Hou (index D). In addition, we analyzed the multiscale multifractal properties of HRV calculating the Hurst surface. The nonlinear analysis methods show statistically significant indications of the risk of AVR surgery in an increase of multifractality and an increase of time irreversibility of the HRV measured prior to the operation. FAU - Zebrowski, J J AU - Zebrowski JJ AD - Complex Systems Division, Faculty of Physics, Warsaw University of Technology, ul. Koszykowa 75, 00-662 Warszawa, Poland. FAU - Kowalik, I AU - Kowalik I FAU - Orlowska-Baranowska, E AU - Orlowska-Baranowska E FAU - Andrzejewska, M AU - Andrzejewska M FAU - Baranowski, R AU - Baranowski R FAU - Gieraltowski, J AU - Gieraltowski J LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20141216 PL - England TA - Physiol Meas JT - Physiological measurement JID - 9306921 SB - IM MH - Aortic Valve/diagnostic imaging/physiopathology/*surgery MH - Aortic Valve Stenosis/diagnostic imaging/mortality/physiopathology/surgery MH - Diabetes Complications/physiopathology MH - Female MH - Heart Rate MH - Heart Valve Prosthesis Implantation/*adverse effects MH - Humans MH - Hypertension/complications/physiopathology MH - Linear Models MH - Male MH - Middle Aged MH - Nonlinear Dynamics MH - Odds Ratio MH - Postoperative Period MH - Risk MH - Risk Assessment/*methods MH - Severity of Illness Index MH - Ultrasonography EDAT- 2014/12/17 06:00 MHDA- 2015/12/17 06:00 CRDT- 2014/12/17 06:00 PHST- 2014/12/17 06:00 [entrez] PHST- 2014/12/17 06:00 [pubmed] PHST- 2015/12/17 06:00 [medline] AID - 10.1088/0967-3334/36/1/163 [doi] PST - ppublish SO - Physiol Meas. 2015 Jan;36(1):163-75. doi: 10.1088/0967-3334/36/1/163. Epub 2014 Dec 16.