PMID- 25515742
OWN - NLM
STAT- MEDLINE
DCOM- 20150910
LR  - 20150119
IS  - 1399-0039 (Electronic)
IS  - 0001-2815 (Linking)
VI  - 85
IP  - 1
DP  - 2015 Jan
TI  - Different patterns of A*80:01:01:01 allele generation based on exon or intron 
      sequences.
PG  - 58-67
LID - 10.1111/tan.12496 [doi]
AB  - Generation of the HLA-A*80:01:01:01 allele has been analysed using its complete 
      sequence. Direct comparison of the sequences and phylogenetic trees using the 
      human leukocyte antigen (HLA)-A representative alleles and the major 
      histocompatibility complex (MHC)-A sequences of non-human primates has been made. 
      Results based on exon sequences confirm previously published, but considering 
      only the sequences of the introns, two distinct regions can be differentiated. 
      The first one comprises from the 5' untranslated region region to the first part 
      of intron 3 sequence (shared with A2 family), and the second one includes the 
      sequence from the end of intron 3 to intron 7 (shared with A1/A3/A11/A36/A30 
      family). Each of them clusters with Gorilla and Chimpanzee MHC-A sequences, 
      respectively, suggesting an origin coming from a common ancestor to Gorilla and 
      Chimpanzee.
CI  - (c) 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - Cervera, I
AU  - Cervera I
AD  - Unidad de Inmunogenetica, Centro Nacional de Microbiologia, Instituto de Salud 
      Carlos III, Madrid, Spain.
FAU - Herraiz, M A
AU  - Herraiz MA
FAU - Vidart, J
AU  - Vidart J
FAU - Ortega, S
AU  - Ortega S
FAU - Martinez-Laso, J
AU  - Martinez-Laso J
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20141217
PL  - England
TA  - Tissue Antigens
JT  - Tissue antigens
JID - 0331072
RN  - 0 (5' Untranslated Regions)
RN  - 0 (HLA-A Antigens)
RN  - 0 (HLA-A*80 Antigen)
RN  - 0 (Protein Isoforms)
SB  - IM
MH  - 5' Untranslated Regions
MH  - *Alleles
MH  - Animals
MH  - Base Sequence
MH  - Biological Evolution
MH  - *Exons
MH  - Gorilla gorilla
MH  - HLA-A Antigens/classification/*genetics/immunology
MH  - Humans
MH  - *Introns
MH  - Molecular Sequence Data
MH  - Pan troglodytes
MH  - *Phylogeny
MH  - Polymorphism, Genetic
MH  - Protein Isoforms/classification/genetics/immunology
OTO - NOTNLM
OT  - HLA-A*80:01:01:01
OT  - evolution
OT  - human leukocyte antigen
OT  - introns
OT  - non-human primates
EDAT- 2014/12/18 06:00
MHDA- 2015/09/12 06:00
CRDT- 2014/12/18 06:00
PHST- 2014/07/14 00:00 [received]
PHST- 2014/11/24 00:00 [revised]
PHST- 2014/11/30 00:00 [accepted]
PHST- 2014/12/18 06:00 [entrez]
PHST- 2014/12/18 06:00 [pubmed]
PHST- 2015/09/12 06:00 [medline]
AID - 10.1111/tan.12496 [doi]
PST - ppublish
SO  - Tissue Antigens. 2015 Jan;85(1):58-67. doi: 10.1111/tan.12496. Epub 2014 Dec 17.