PMID- 25531976 OWN - NLM STAT- MEDLINE DCOM- 20151029 LR - 20150213 IS - 1421-9697 (Electronic) IS - 0250-6807 (Linking) VI - 66 IP - 1 DP - 2015 TI - Composition of dietary macronutrient intake is not associated with prevalence of coronary artery calcification in healthy Korean adults. PG - 36-43 LID - 10.1159/000369563 [doi] AB - BACKGROUND AND AIMS: There is little information supporting the relationships between macronutrients and pre-clinical atherosclerosis. The aim of this study was to identify whether dietary macronutrient content is related with CAC. METHODS: 10,793 healthy Korean adults in a cohort were enrolled. Subjects were divided into CAC (CAC score >0) or non-CAC group (CAC score = 0). Intake of energy, carbohydrate (CHO), protein and fat were obtained using food frequency questionnaire (FFQ). Macronutrient composition was expressed as the ratio of energy from each macronutrient to total energy. Subjects were classified into three groups according to tertiles of intake for each macronutrient. To investigate the association between macronutrient intake and CAC, multiple regression analysis was conducted according to tertile groups of each macronutrient. RESULTS: The prevalence of CAC significantly differed among tertile groups of CHO and fat intake in men (p < 0.001, p < 0.01) and women (p < 0.05, p < 0.01). However, multiple logistic regression analysis revealed that the odds ratios (ORs) for CAC were not significantly different among tertile groups of each macronutrient intake after adjustment in men (CHO: OR = 0.965 [95% CI = 0.826-1.129]; protein: OR = 1.029 [95% CI = 0.881-1.201]; fat: OR = 1.015 [95% CI = 0.868-1.188]) and women (CHO: OR = 1.158 [95% CI = 0.550-2.438]; protein: OR = 1.261 [95% CI = 0.629-2.528]; fat: OR = 0.625 [95% CI = 0.286-1.365]). CONCLUSIONS: The prevalence of CAC may not be associated with composition of dietary macronutrient intake in in healthy Korean adults. CI - (c) 2014 S. Karger AG, Basel. FAU - Sung, Ki-Chul AU - Sung KC AD - Division of Cardiology, Department of Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. FAU - Sung, Eunju AU - Sung E FAU - Byrne, Christopher D AU - Byrne CD FAU - Kim, Yong Bum AU - Kim YB FAU - Ahn, Chul Woo AU - Ahn CW FAU - Chung, Hye-Kyung AU - Chung HK LA - eng PT - Journal Article DEP - 20141213 PL - Switzerland TA - Ann Nutr Metab JT - Annals of nutrition & metabolism JID - 8105511 RN - 0 (Dietary Carbohydrates) RN - 0 (Dietary Fats) RN - 0 (Dietary Proteins) SB - IM MH - Adult MH - Calcinosis/*etiology MH - Cohort Studies MH - Coronary Artery Disease/epidemiology/*etiology MH - *Dietary Carbohydrates MH - *Dietary Fats MH - *Dietary Proteins MH - *Energy Intake MH - Female MH - Humans MH - Korea/epidemiology MH - Male MH - Middle Aged MH - Prevalence MH - Regression Analysis MH - Risk Factors EDAT- 2014/12/23 06:00 MHDA- 2015/10/30 06:00 CRDT- 2014/12/23 06:00 PHST- 2014/07/16 00:00 [received] PHST- 2014/11/03 00:00 [accepted] PHST- 2014/12/23 06:00 [entrez] PHST- 2014/12/23 06:00 [pubmed] PHST- 2015/10/30 06:00 [medline] AID - 000369563 [pii] AID - 10.1159/000369563 [doi] PST - ppublish SO - Ann Nutr Metab. 2015;66(1):36-43. doi: 10.1159/000369563. Epub 2014 Dec 13.