PMID- 25535719 OWN - NLM STAT- MEDLINE DCOM- 20160222 LR - 20141224 IS - 1165-158X (Electronic) IS - 0145-5680 (Linking) VI - 60 IP - 5 DP - 2014 Dec 24 TI - Histone demethylases and control of gene expression in plants. PG - 97-105 AB - Covalent histone modifications, chromatin remodeling and incorporation of histone variants regulate the dynamics of chromatin structure. Among covalent histone modifications, histone methylation mediates by histone methylases that influence the gene expression in heterochromatin silencing, genomic imprinting and transcription. In contrast to methylases, histone demethylases remove the methyl groups from lysine or arginine residues of histones and have enormous impact on gene expression via modified chromatin structures. Two types of histone lysie demethylases have been identified, including lysine specific demethylases 1 (LSD1) and Jmj (Jumonji) domain containing family proteins. The human demethyliminase (PADI4) converts monomethyl arginine residue to citrulline by the arginine demethylimination. In this review we summarize recent advances to understand the mechanism of demethylases in regulation of plant gene expression. In addition we are highlighting the function of four human like LSD1 (LDL) and jmj domain containing genes of Arabidopsis that regulate the defense related, flowering controlling and brassinosteroid response genes. FAU - Prakash, S AU - Prakash S AD - University of Warwick Synthetic Biology, School of life science Coventry United Kingdom. FAU - Singh, R AU - Singh R AD - National Research Center on Equines Haryana India. FAU - Lodhi, N AU - Lodhi N AD - Fox Chase Cancer Center Philadelphia USA lodhiniraj@gmail.com. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PT - Review DEP - 20141224 PL - France TA - Cell Mol Biol (Noisy-le-grand) JT - Cellular and molecular biology (Noisy-le-Grand, France) JID - 9216789 RN - 0 (Plant Proteins) RN - EC 1.14.11.- (Histone Demethylases) SB - IM MH - DNA Methylation MH - *Gene Expression Regulation, Plant MH - Histone Demethylases/chemistry/genetics/*metabolism MH - Humans MH - Plant Proteins/chemistry/genetics/*metabolism MH - Plants/*enzymology/*genetics/metabolism MH - Protein Conformation EDAT- 2014/12/24 06:00 MHDA- 2016/02/24 06:00 CRDT- 2014/12/24 06:00 PHST- 2014/07/08 00:00 [received] PHST- 2014/07/15 00:00 [accepted] PHST- 2014/12/24 06:00 [entrez] PHST- 2014/12/24 06:00 [pubmed] PHST- 2016/02/24 06:00 [medline] PST - epublish SO - Cell Mol Biol (Noisy-le-grand). 2014 Dec 24;60(5):97-105.