PMID- 25538027 OWN - NLM STAT- MEDLINE DCOM- 20180221 LR - 20181202 IS - 1097-0347 (Electronic) IS - 1043-3074 (Linking) VI - 38 Suppl 1 DP - 2016 Apr TI - Treatment outcomes of intensity-modulated radiotherapy versus 3D conformal radiotherapy for patients with maxillary sinus cancer in the postoperative setting. PG - E207-13 LID - 10.1002/hed.23971 [doi] AB - BACKGROUND: In this study, we compared the treatment outcomes of postoperative 3D conformal radiotherapy (RT) and intensity-modulated radiotherapy (IMRT) for patients with maxillary sinus carcinoma. METHODS: Fifty-four patients underwent surgery and postoperative RT, of whom 27 (50%) had squamous cell carcinoma and 14 (26%) had adenoid cystic carcinoma. Nineteen patients (35%) were treated with IMRT and 35 patients (65%) received 3D conformal RT. The median radiation dose for 3D conformal RT and IMRT were 62.1 and 63 Gy, respectively. RESULTS: IMRT produced significantly superior radiation dose distribution to planning target volumes (PTVs) than 3D conformal RT. Over a median follow-up of 60 months, IMRT provided better 3-year locoregional recurrence-free survival (89.2% vs 59.5%; p = .035) and distant metastasis-free survival (94.7% vs 55.3%; p = .042) rates than 3D conformal RT. CONCLUSION: Postoperative IMRT for patients with maxillary sinus carcinoma resulted in excellent disease control, and should be considered as the first treatment option in these cases. (c) 2015 Wiley Periodicals, Inc. Head Neck 38: E207-E213, 2016. CI - (c) 2015 Wiley Periodicals, Inc. FAU - Suh, Yang-Gun AU - Suh YG AD - Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Republic of Korea. FAU - Lee, Chang Geol AU - Lee CG AD - Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Republic of Korea. FAU - Kim, Hyunju AU - Kim H AD - Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Republic of Korea. FAU - Choi, Eun Chang AU - Choi EC AD - Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea. FAU - Kim, Se Hun AU - Kim SH AD - Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea. FAU - Kim, Chang-Hoon AU - Kim CH AD - Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul, Republic of Korea. FAU - Keum, Ki Chang AU - Keum KC AD - Department of Radiation Oncology, Yonsei University College of Medicine, Seoul, Republic of Korea. LA - eng PT - Comparative Study PT - Journal Article DEP - 20150604 PL - United States TA - Head Neck JT - Head & neck JID - 8902541 SB - IM MH - Adult MH - Aged MH - Carcinoma, Adenoid Cystic/radiotherapy MH - Carcinoma, Squamous Cell/radiotherapy MH - Female MH - Humans MH - Male MH - Maxillary Sinus Neoplasms/*radiotherapy MH - Middle Aged MH - Radiotherapy Dosage MH - *Radiotherapy, Conformal MH - *Radiotherapy, Intensity-Modulated MH - Treatment Outcome OTO - NOTNLM OT - 3D conformal radiotherapy (RT) OT - intensity-modulated radiotherapy (IMRT) OT - maxillary sinus cancer OT - maxillectomy OT - paranasal sinus EDAT- 2014/12/30 06:00 MHDA- 2018/02/22 06:00 CRDT- 2014/12/25 06:00 PHST- 2014/03/18 00:00 [received] PHST- 2014/10/15 00:00 [revised] PHST- 2014/12/17 00:00 [accepted] PHST- 2014/12/25 06:00 [entrez] PHST- 2014/12/30 06:00 [pubmed] PHST- 2018/02/22 06:00 [medline] AID - 10.1002/hed.23971 [doi] PST - ppublish SO - Head Neck. 2016 Apr;38 Suppl 1:E207-13. doi: 10.1002/hed.23971. Epub 2015 Jun 4.