PMID- 25542342 OWN - NLM STAT- MEDLINE DCOM- 20151001 LR - 20221207 IS - 1873-2585 (Electronic) IS - 1047-2797 (Print) IS - 1047-2797 (Linking) VI - 25 IP - 2 DP - 2015 Feb TI - Influence of residential segregation on survival after AIDS diagnosis among non-Hispanic blacks. PG - 113-9, 119.e1 LID - S1047-2797(14)00528-6 [pii] LID - 10.1016/j.annepidem.2014.11.023 [doi] AB - PURPOSE: Non-Hispanic blacks (NHBs) are disproportionately affected by the AIDS epidemic. With the advent of highly active antiretroviral therapy (HAART), survival after AIDS diagnosis has increased dramatically, yet survival among NHBs is shorter compared with non-Hispanic whites. Racial residential segregation may be an important factor influencing observed racial disparities in survival. METHODS: We linked data on 30,813 NHBs from the Florida Department of Health HIV/AIDS Reporting system (1993-2004) with death records and applied segregation indices and poverty levels to the data. Weighted Cox models were used to examine the association between segregation measured on five dimensions and survival, controlling for demographic factors, clinical factors, and area-level poverty. Analyses were stratified by pre-HAART (1993-1995), early HAART (1996-1998), and late-HAART (1999-2004) eras. RESULTS: In the late-HAART era, adjusting for area-level poverty, segregation remained a significant predictor of survival on two dimensions: Concentration (hazard ratio, 1.32; 95% confidence interval, 1.13-1.56) and centralization (hazard ratio, 1.44; 95% confidence interval, 1.12-1.84). Area-level poverty was an independent predictor of survival. CONCLUSIONS: These findings suggest that certain dimensions of segregation and poverty are associated with survival after AIDS diagnosis. CI - Copyright (c) 2015 Elsevier Inc. All rights reserved. FAU - Fennie, Kristopher P AU - Fennie KP AD - Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, Miami. Electronic address: kfennie@fiu.edu. FAU - Lutfi, Khaleeq AU - Lutfi K AD - Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, Miami. FAU - Maddox, Lorene M AU - Maddox LM AD - Florida Consortium for HIV/AIDS Research/The AIDS Institute, Tampa. FAU - Lieb, Spencer AU - Lieb S AD - HIV/AIDS Section, Florida Department of Health, Tallahassee. FAU - Trepka, Mary Jo AU - Trepka MJ AD - Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, Miami. LA - eng GR - R01 MD004002/MD/NIMHD NIH HHS/United States GR - R01MD004002/MD/NIMHD NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20141128 PL - United States TA - Ann Epidemiol JT - Annals of epidemiology JID - 9100013 SB - IM MH - Acquired Immunodeficiency Syndrome/drug therapy/*ethnology/*mortality MH - Adult MH - Black or African American/*statistics & numerical data MH - Antiretroviral Therapy, Highly Active MH - Female MH - Florida/epidemiology MH - Housing/statistics & numerical data MH - Humans MH - Male MH - Middle Aged MH - Poverty/statistics & numerical data MH - Racism/*statistics & numerical data MH - Residence Characteristics/*statistics & numerical data PMC - PMC4415530 MID - NIHMS651786 OTO - NOTNLM OT - Acquired immune deficiency Syndrome OT - African Americans OT - HIV OT - Racism OT - Survival EDAT- 2014/12/30 06:00 MHDA- 2015/10/02 06:00 PMCR- 2016/02/01 CRDT- 2014/12/28 06:00 PHST- 2014/04/22 00:00 [received] PHST- 2014/08/29 00:00 [revised] PHST- 2014/11/04 00:00 [accepted] PHST- 2014/12/28 06:00 [entrez] PHST- 2014/12/30 06:00 [pubmed] PHST- 2015/10/02 06:00 [medline] PHST- 2016/02/01 00:00 [pmc-release] AID - S1047-2797(14)00528-6 [pii] AID - 10.1016/j.annepidem.2014.11.023 [doi] PST - ppublish SO - Ann Epidemiol. 2015 Feb;25(2):113-9, 119.e1. doi: 10.1016/j.annepidem.2014.11.023. Epub 2014 Nov 28.