PMID- 25544931
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20141229
LR  - 20200929
IS  - 2090-8016 (Print)
IS  - 2090-0597 (Electronic)
IS  - 2090-0597 (Linking)
VI  - 2014
DP  - 2014
TI  - Exercise Hemodynamics and Quality of Life after Aortic Valve Replacement for 
      Aortic Stenosis in the Elderly Using the Hancock II Bioprosthesis.
PG  - 151282
LID - 10.1155/2014/151282 [doi]
LID - 151282
AB  - Background and Aim. While aortic valve replacement for aortic stenosis can be 
      performed safely in elderly patients, there is a need for hemodynamic and quality 
      of life evaluation to determine the value of aortic valve replacement in older 
      patients who may have age-related activity limitation. Materials and Methods. We 
      conducted a prospective evaluation of patients who underwent aortic valve 
      replacement for aortic stenosis with the Hancock II porcine bioprosthesis. All 
      patients underwent transthoracic echocardiography (TTE) and completed the RAND 
      36-Item Health Survey (SF-36) preoperatively and six months postoperatively. 
      Results. From 2004 to 2007, 33 patients were enrolled with an average age of 
      75.3 +/- 5.3 years (24 men and 9 women). Preoperatively, 27/33 (82%) were New York 
      Heart Association (NYHA) Functional Classification 3, and postoperatively 27/33 
      (82%) were NYHA Functional Classification 1. Patients had a mean predicted 
      maximum V O2 (mL/kg/min) of 19.5 +/- 4.3 and an actual max V O2 of 15.5 +/- 3.9, 
      which was 80% of the predicted V O2 . Patients were found to have significant 
      improvements (P </= 0.01) in six of the nine SF-36 health parameters. Conclusions. 
      In our sample of elderly patients with aortic stenosis, replacing the aortic 
      valve with a Hancock II bioprosthesis resulted in improved hemodynamics and 
      quality of life.
FAU - Long, Theodore
AU  - Long T
AD  - Robert Wood Johnson Clinical Scholars Program, Department of Internal Medicine, 
      Yale School of Medicine, New Haven, CT 06520, USA.
FAU - Lopez, Becky M
AU  - Lopez BM
AD  - Department of Cardiothoracic Surgery, Keck School of Medicine, University of 
      Southern California, Los Angeles, CA 90033, USA.
FAU - Berberian, Christopher
AU  - Berberian C
AD  - Department of Cardiothoracic Surgery, Keck School of Medicine, University of 
      Southern California, Los Angeles, CA 90033, USA.
FAU - Cunningham, Mark J
AU  - Cunningham MJ
AD  - Department of Cardiothoracic Surgery, Keck School of Medicine, University of 
      Southern California, Los Angeles, CA 90033, USA.
FAU - Starnes, Vaughn A
AU  - Starnes VA
AD  - Department of Cardiothoracic Surgery, Keck School of Medicine, University of 
      Southern California, Los Angeles, CA 90033, USA.
FAU - Cohen, Robbin G
AU  - Cohen RG
AD  - Department of Cardiothoracic Surgery, Keck School of Medicine, University of 
      Southern California, Los Angeles, CA 90033, USA ; USC Healthcare Consultation 
      Center II, 1520 San Pablo Street, Suite 4300, Los Angeles, CA 90033, USA.
LA  - eng
PT  - Journal Article
DEP - 20141202
PL  - United States
TA  - Cardiol Res Pract
JT  - Cardiology research and practice
JID - 101516542
PMC - PMC4269201
EDAT- 2014/12/30 06:00
MHDA- 2014/12/30 06:01
PMCR- 2014/12/02
CRDT- 2014/12/30 06:00
PHST- 2014/07/04 00:00 [received]
PHST- 2014/09/30 00:00 [revised]
PHST- 2014/10/18 00:00 [accepted]
PHST- 2014/12/30 06:00 [entrez]
PHST- 2014/12/30 06:00 [pubmed]
PHST- 2014/12/30 06:01 [medline]
PHST- 2014/12/02 00:00 [pmc-release]
AID - 10.1155/2014/151282 [doi]
PST - ppublish
SO  - Cardiol Res Pract. 2014;2014:151282. doi: 10.1155/2014/151282. Epub 2014 Dec 2.