PMID- 25545711
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150126
LR  - 20200929
IS  - 2210-2612 (Print)
IS  - 2210-2612 (Electronic)
IS  - 2210-2612 (Linking)
VI  - 6C
DP  - 2015
TI  - Massive intrathoracic lipoma in men1 syndrome.
PG  - 247-50
LID - S2210-2612(14)00322-8 [pii]
LID - 10.1016/j.ijscr.2014.10.071 [doi]
AB  - INTRODUCTION: The multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal 
      dominant syndrome characterized by the onset of hyperparathyroidism, 
      gastroenteropancreatic neuroendocrine tumors and pituitary lesions. PRESENTATION 
      OF CASE: This appears to be the first described case of a massive intrathoracic 
      lipoma in MEN1. The patient was affected with primary hyperparathyroidism treated 
      with a total parathyroidectomy followed by a distal pancreatectomy for 
      insulinoma. At follow-up, the computed tomography showed a massive lesion on the 
      left emithorax suggestive of a lipoma. At the onset of a mild dyspnea we decided 
      to perform the surgical excision of the mass obtaining a complete relief of the 
      symptoms. DISCUSSION: This case is evidence of the importance of a strict 
      follow-up of such patients. CONCLUSION: Lipomas are the most frequent benign soft 
      tissue tumors. They are usually sporadic but are sometimes related to hereditary 
      syndromes. Intrathoracic localizations are rare and can arise mainly in the 
      mediastinum, bronchus or lung. The diagnosis is often incidental; despite 
      preoperative imaging will accurately show the features of the lesions, it is 
      impossible obtain an accurate diagnosis-hence, the treatment of choice remains 
      the surgical excision.
CI  - Copyright (c) 2014 The Authors. Published by Elsevier Ltd.. All rights reserved.
FAU - Sturiale, Alessandro
AU  - Sturiale A
AD  - Digestive Surgery Unit, Department of Surgery and Translational Medicine, 
      University of Florence Medical School, Careggi University Hospital, Florence, 
      Italy. Electronic address: alexstur@yahoo.it.
FAU - Giudici, Francesco
AU  - Giudici F
AD  - Digestive Surgery Unit, Department of Surgery and Translational Medicine, 
      University of Florence Medical School, Careggi University Hospital, Florence, 
      Italy.
FAU - Alemanno, Giovanni
AU  - Alemanno G
AD  - Digestive Surgery Unit, Department of Surgery and Translational Medicine, 
      University of Florence Medical School, Careggi University Hospital, Florence, 
      Italy.
FAU - Cavalli, Tiziana
AU  - Cavalli T
AD  - Digestive Surgery Unit, Department of Surgery and Translational Medicine, 
      University of Florence Medical School, Careggi University Hospital, Florence, 
      Italy.
FAU - Addasi, Rami
AU  - Addasi R
AD  - Digestive Surgery Unit, Department of Surgery and Translational Medicine, 
      University of Florence Medical School, Careggi University Hospital, Florence, 
      Italy.
FAU - Santomaggio, Carmine
AU  - Santomaggio C
AD  - Department of Pneumology, University of Florence Medical School, Careggi 
      University Hospital, Florence, Italy.
FAU - Meoni, Giulia
AU  - Meoni G
AD  - Department of Oncology, Medical Oncology 1, Careggi University Hospital, 
      Florence, Italy.
FAU - Brandi, Maria Luisa
AU  - Brandi ML
AD  - Regional Centre for Hereditary Endocrine Tumors, Unit of Metabolic Bone Diseases, 
      Department of Internal Medicine, University of Florence, Florence, Italy.
FAU - Tonelli, Francesco
AU  - Tonelli F
AD  - Digestive Surgery Unit, Department of Surgery and Translational Medicine, 
      University of Florence Medical School, Careggi University Hospital, Florence, 
      Italy.
LA  - eng
PT  - Journal Article
DEP - 20141212
PL  - Netherlands
TA  - Int J Surg Case Rep
JT  - International journal of surgery case reports
JID - 101529872
PMC - PMC4337913
OTO - NOTNLM
OT  - GEP-NET
OT  - Intrathoracic lipoma
OT  - MEN 1 syndrome
OT  - Surgery
EDAT- 2014/12/30 06:00
MHDA- 2014/12/30 06:01
PMCR- 2014/12/12
CRDT- 2014/12/30 06:00
PHST- 2014/02/24 00:00 [received]
PHST- 2014/10/17 00:00 [revised]
PHST- 2014/10/18 00:00 [accepted]
PHST- 2014/12/30 06:00 [entrez]
PHST- 2014/12/30 06:00 [pubmed]
PHST- 2014/12/30 06:01 [medline]
PHST- 2014/12/12 00:00 [pmc-release]
AID - S2210-2612(14)00322-8 [pii]
AID - 10.1016/j.ijscr.2014.10.071 [doi]
PST - ppublish
SO  - Int J Surg Case Rep. 2015;6C:247-50. doi: 10.1016/j.ijscr.2014.10.071. Epub 2014 
      Dec 12.