PMID- 25548025 OWN - NLM STAT- MEDLINE DCOM- 20151214 LR - 20231110 IS - 1879-0046 (Electronic) IS - 0376-8716 (Print) IS - 0376-8716 (Linking) VI - 147 DP - 2015 Feb 1 TI - Prevalence and correlates of substance use among trans female youth ages 16-24 years in the San Francisco Bay Area. PG - 160-6 LID - S0376-8716(14)01936-X [pii] LID - 10.1016/j.drugalcdep.2014.11.023 [doi] AB - BACKGROUND: Substance use is highly prevalent among transgender (trans*) females and has been associated with negative health outcomes, including HIV infection. Little is known about psychosocial risk factors that may influence the onset of substance use among trans*female youth, which can contribute to health disparities during adulthood. METHODS: We conducted a secondary data analysis of a study on HIV risk and resilience among trans*female youth (N=292). Prevalence of substance use was assessed and multivariable logistic regression models were used to examine the relationship between posttraumatic stress disorder (PTSD), psychological distress, gender-related discrimination, parental drug or alcohol problems (PDAP) and multiple substance use outcomes. RESULTS: Most (69%) of the trans*female youth reported recent drug use. In multivariable analyses, those with PTSD had increased odds of drug use [AOR=1.94 (95% CI=1.09-3.44)]. Those who experienced gender-related discrimination had increased odds of drug use [AOR=2.28 (95% CI=1.17-4.44)], drug use concurrent with sex [AOR=2.35 (95% CI=1.11-4.98)] and use of multiple drugs [AOR=3.24 (95% CI=1.52-6.88)]. Those with psychological distress had increased odds of using multiple heavy drugs [AOR=2.27 (95% CI=1.01-5.12)]. Those with PDAP had increased odds of drugs use [AOR=2.62 (95% CI=1.43-4.82)], drug use concurrent with sex [AOR=2.01 (95% CI, 1.15-3.51)] and use of multiple drugs [AOR=2.10 (95% CI=1.22-3.62)]. CONCLUSIONS: Substance use is highly prevalent among trans*female youth and was significantly associated with psychosocial risk factors. In order to effectively address substance use among trans*female youth, efforts must address coping related to gender-based discrimination and trauma. Furthermore, structural level interventions aiming to reduce stigma and gender-identity discrimination might also be effective. CI - Copyright (c) 2014 Elsevier Ireland Ltd. All rights reserved. FAU - Rowe, Chris AU - Rowe C AD - Center for Public Health Research, San Francisco Department of Public Health, 25 Van Ness Avenue, San Francisco, CA 94102, United States. FAU - Santos, Glenn-Milo AU - Santos GM AD - Center for Public Health Research, San Francisco Department of Public Health, 25 Van Ness Avenue, San Francisco, CA 94102, United States. FAU - McFarland, Willi AU - McFarland W AD - Center for Public Health Research, San Francisco Department of Public Health, 25 Van Ness Avenue, San Francisco, CA 94102, United States. FAU - Wilson, Erin C AU - Wilson EC AD - Center for Public Health Research, San Francisco Department of Public Health, 25 Van Ness Avenue, San Francisco, CA 94102, United States. Electronic address: erincwilson@gmail.com. LA - eng GR - P30 MH062246/MH/NIMH NIH HHS/United States GR - R01 MH095598/MH/NIMH NIH HHS/United States GR - R01MH095598/MH/NIMH NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20141215 PL - Ireland TA - Drug Alcohol Depend JT - Drug and alcohol dependence JID - 7513587 SB - IM MH - Adolescent MH - Alcoholism/complications/epidemiology MH - Female MH - Gender Identity MH - HIV Infections/complications/epidemiology MH - Humans MH - Mental Disorders/complications/epidemiology MH - Prevalence MH - Risk Factors MH - San Francisco/epidemiology MH - Socioeconomic Factors MH - Substance-Related Disorders/*epidemiology MH - Transgender Persons/*statistics & numerical data MH - Treatment Outcome MH - Young Adult PMC - PMC4297727 MID - NIHMS650663 OTO - NOTNLM OT - Discrimination OT - Health disparities OT - Posttraumatic stress disorder OT - Substance use OT - Trans*female youth OT - Transgender COIS- Conflict of Interest. No conflict declared EDAT- 2014/12/31 06:00 MHDA- 2015/12/15 06:00 PMCR- 2016/02/01 CRDT- 2014/12/31 06:00 PHST- 2014/07/25 00:00 [received] PHST- 2014/11/20 00:00 [revised] PHST- 2014/11/21 00:00 [accepted] PHST- 2014/12/31 06:00 [entrez] PHST- 2014/12/31 06:00 [pubmed] PHST- 2015/12/15 06:00 [medline] PHST- 2016/02/01 00:00 [pmc-release] AID - S0376-8716(14)01936-X [pii] AID - 10.1016/j.drugalcdep.2014.11.023 [doi] PST - ppublish SO - Drug Alcohol Depend. 2015 Feb 1;147:160-6. doi: 10.1016/j.drugalcdep.2014.11.023. Epub 2014 Dec 15.