PMID- 25555860 OWN - NLM STAT- MEDLINE DCOM- 20150817 LR - 20181202 IS - 2284-0729 (Electronic) IS - 1128-3602 (Linking) VI - 18 IP - 24 DP - 2014 TI - Comparison of cerebral-cardiac syndrome caused by nonaneurysmal or aneurysmal subarachnoid hemorrhage. PG - 3737-42 LID - 8245 [pii] AB - OBJECTIVE: To investigate the difference between myocardial injuries caused by nonaneurysmal subarachnoid hemorrhage (SAH) or aneurysmal SAH. PATIENTS AND METHODS: A total of 92 inpatients with SAH at early stage (within 48h), who were treated in our hospital from 2008 to 2014 were enrolled in this study. Differences in cerebral-cardiac syndrome seen in perimesencephalic subarachnoid hemorrhage (PMSAH), non-perimesencephalic subarachnoid hemorrhage (n-PMSAH), and aneurysmal subarachnoid hemorrhage (aSAH) were recorded based Hunt-Hess scores, electrocardiogram/echocardiography findings, and serum myocardial enzymes. RESULTS: The Hunt-Hess grade was relatively lower in the PMSAH group (mainly at grades I and II) than in aSAH group and n-PMSAH group. The ECG score was significantly lower in the PMSAH Group than in the aSAH or n-PMSAH Group. In the PMSAH group, the left ventricular function was normal; in contrast, the left ventricular end-systolic diameter, left ventricular end-diastolic diameter, left ventricular wall thickness, and left ventricular ejection fraction showed certain abnormalities in the aSAH group and n-PMSAH group. The myocardial enzymes remarkably increased only in the aSAH group. CONCLUSIONS: In PMSAH patients, the lower Hunt-Hess grade, milder ECG abnormalities, less changes in cardiac enzymes and echocardiography are associated with better prognosis. The clinical course and myocardial injuries are poorer in n-PMSAH patients when compared with the PMSAH patients but better than aSAH patients. FAU - Huang, W-J AU - Huang WJ AD - Department of Neurology, Xuzhou Central Hospital, Xuzhou, Jiangsu Province, China. baogaozx@163.com. FAU - Chen, W-W AU - Chen WW FAU - Zhang, X AU - Zhang X LA - eng PT - Comparative Study PT - Journal Article PL - Italy TA - Eur Rev Med Pharmacol Sci JT - European review for medical and pharmacological sciences JID - 9717360 SB - IM MH - Adult MH - Aged MH - Cardiovascular Diseases/*diagnosis/etiology/*physiopathology MH - Electrocardiography/methods MH - Female MH - Humans MH - Intracranial Aneurysm/complications/*diagnosis/*physiopathology MH - Male MH - Middle Aged MH - Stroke Volume/physiology MH - Subarachnoid Hemorrhage/complications/*diagnosis/*physiopathology MH - Syndrome MH - Ventricular Function, Left/physiology EDAT- 2015/01/06 06:00 MHDA- 2015/08/19 06:00 CRDT- 2015/01/04 06:00 PHST- 2015/01/04 06:00 [entrez] PHST- 2015/01/06 06:00 [pubmed] PHST- 2015/08/19 06:00 [medline] AID - 8245 [pii] PST - ppublish SO - Eur Rev Med Pharmacol Sci. 2014;18(24):3737-42.