PMID- 25556906 OWN - NLM STAT- MEDLINE DCOM- 20160613 LR - 20161125 IS - 1540-8175 (Electronic) IS - 0742-2822 (Linking) VI - 32 IP - 9 DP - 2015 Sep TI - Novel Echocardiographic Indices as Predictors of Immediate Recurrence after Undersized Ring Annuloplasty for Ischemic Mitral Regurgitation. PG - 1339-46 LID - 10.1111/echo.12879 [doi] AB - BACKGROUND AND AIM: Ischemic mitral regurgitation (IMR) is among the most serious complications of myocardial infarction which doubles the late mortality; mainly treated by undersizing ring annuloplasty. To find some preoperative echocardiographic indices that predict immediate failure of mitral valve annuloplasty (MVA), we designed the present study with more focusing on some novel parameters. METHOD: Transthoracic echocardiography (TTE) indices of consecutive patients referred with 3+ or 4+ IMR were registered 24 hours before surgery. Thirty days later, a second TTE was performed. According to the results, the patients were categorized as the "successful" group (with 1+ or less mitral regurgitation) and the "unsuccessful" group (with 2+ or higher MR). Preoperative TTE indices were compared among the two groups using suitable statistical tests. RESULTS: Of the total of 126 cases, 68 had successful and 58 had unsuccessful MVA. Statistically significant differences were found between the two groups for left ventricular ejection fraction (LVEF) (P = 0.007), left ventricular end systolic volume (LVESV) (P = 0.044), and basal-interpapillary muscle distance (IPMD) diastolic-to-systolic ratio (DSR) (P = 0.008). Receiver Operating Characteristic analysis demonstrated 37.5%, 3.85 cm(3) , and 1.25, as the best cutoff points for LVEF (P = 0.03, sensitivity: 81%, specificity: 69%), LVESV (P = 0.023, sensitivity: 83%, specificity: 57%), and basal-IPMD DSR (P = 0.001, sensitivity: 100%, specificity: 95%), respectively. CONCLUSION: Among all TTE indices, LVEF, LVESV, and basal-IPMD DSR were helpful to differentiate between the successful and unsuccessful MVA results. We believe the basal-IPMD DSR as a novel index could be targeted in the future studies. CI - (c) 2015, Wiley Periodicals, Inc. FAU - Hajsadeghi, Shokoufeh AU - Hajsadeghi S AD - Department of Cardiology, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. FAU - Samiee, Niloufar AU - Samiee N AD - Department of Cardiology, Shahid Rajaee Heart Hospital, Iran University of Medical Sciences, Tehran, Iran. FAU - Hosseini, Seyyed Saied AU - Hosseini SS AD - Department of Cardiac Surgery, Heart Valve Research Center, Shahid Rajaee Heart Hospital, Iran University of Medical Sciences, Tehran, Iran. FAU - Hassanzadeh, Morteza AU - Hassanzadeh M AD - Department of Internal Medicine, Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. FAU - Kerman, Scott Reza Jafarian AU - Kerman SR AD - Department of Cardiology, Student Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran. LA - eng PT - Journal Article DEP - 20150102 PL - United States TA - Echocardiography JT - Echocardiography (Mount Kisco, N.Y.) JID - 8511187 SB - IM MH - Aged MH - Female MH - Follow-Up Studies MH - *Heart Valve Prosthesis Implantation MH - Humans MH - Male MH - Middle Aged MH - Mitral Valve/diagnostic imaging/surgery MH - *Mitral Valve Annuloplasty MH - Mitral Valve Insufficiency/*diagnostic imaging/*surgery MH - Postoperative Complications/*diagnostic imaging MH - Recurrence MH - Treatment Outcome MH - Ultrasonography OTO - NOTNLM OT - echocardiography OT - immediate recurrence OT - ischemic mitral regurgitation OT - ring annuloplasty EDAT- 2015/01/06 06:00 MHDA- 2016/06/14 06:00 CRDT- 2015/01/06 06:00 PHST- 2015/01/06 06:00 [entrez] PHST- 2015/01/06 06:00 [pubmed] PHST- 2016/06/14 06:00 [medline] AID - 10.1111/echo.12879 [doi] PST - ppublish SO - Echocardiography. 2015 Sep;32(9):1339-46. doi: 10.1111/echo.12879. Epub 2015 Jan 2.