PMID- 25565440
OWN - NLM
STAT- MEDLINE
DCOM- 20150409
LR  - 20220408
IS  - 2041-5990 (Print)
IS  - 2041-5990 (Linking)
VI  - 6
IP  - 1
DP  - 2015 Jan
TI  - PLGA: a unique polymer for drug delivery.
PG  - 41-58
LID - 10.4155/tde.14.91 [doi]
AB  - Biodegradable polymers have played an important role in the delivery of drugs in 
      a controlled and targeted manner. Polylactic-co-glycolic acid (PLGA) is one of 
      the extensively researched synthetic biodegradable polymers due to its favorable 
      properties. It is also known as a 'Smart Polymer' due to its stimuli sensitive 
      behavior. A wide range of PLGA-based drug delivery systems have been reported for 
      the treatment or diagnosis of various diseases and disorders. The present review 
      provides an overview of the chemistry, physicochemical properties, biodegradation 
      behavior, evaluation parameters and applications of PLGA in drug delivery. 
      Different drug-polymer combinations developed into drug delivery or carrier 
      systems are enumerated and discussed.
FAU - Kapoor, Deepak N
AU  - Kapoor DN
AD  - School of Pharmaceutical Sciences (LSPS), Faculty of Applied Medical Sciences 
      (LFAMS), Lovely Professional University (LPU), Phagwara, Punjab, India.
FAU - Bhatia, Amit
AU  - Bhatia A
FAU - Kaur, Ripandeep
AU  - Kaur R
FAU - Sharma, Ruchi
AU  - Sharma R
FAU - Kaur, Gurvinder
AU  - Kaur G
FAU - Dhawan, Sanju
AU  - Dhawan S
LA  - eng
PT  - Journal Article
PT  - Review
PL  - England
TA  - Ther Deliv
JT  - Therapeutic delivery
JID - 101538870
RN  - 1SIA8062RS (Polylactic Acid-Polyglycolic Acid Copolymer)
RN  - 26009-03-0 (Polyglycolic Acid)
RN  - 33X04XA5AT (Lactic Acid)
SB  - IM
MH  - Biodegradation, Environmental
MH  - *Drug Delivery Systems
MH  - *Lactic Acid/chemical synthesis/chemistry
MH  - Nanoparticles
MH  - *Polyglycolic Acid/chemical synthesis/chemistry
MH  - Polylactic Acid-Polyglycolic Acid Copolymer
EDAT- 2015/01/08 06:00
MHDA- 2015/04/10 06:00
CRDT- 2015/01/08 06:00
PHST- 2015/01/08 06:00 [entrez]
PHST- 2015/01/08 06:00 [pubmed]
PHST- 2015/04/10 06:00 [medline]
AID - 10.4155/tde.14.91 [doi]
PST - ppublish
SO  - Ther Deliv. 2015 Jan;6(1):41-58. doi: 10.4155/tde.14.91.