PMID- 25566709 OWN - NLM STAT- MEDLINE DCOM- 20150908 LR - 20181113 IS - 0974-5181 (Electronic) IS - 0971-9784 (Print) IS - 0971-9784 (Linking) VI - 18 IP - 1 DP - 2015 Jan-Mar TI - Efficacy of cardiac resynchronization with defibrillator insertion in patients undergone coronary artery bypass graft: a cohort study of cardiac function. PG - 34-8 LID - 10.4103/0971-9784.148319 [doi] AB - INTRODUCTION: Cardiac resynchronization therapy (CRT) is a proven therapeutic method in selected patients with heart failure and systolic dysfunction which increases left ventricular function and patient survival. We designed a study that included patients undergoing coronary artery bypass graft (CABG), with and without CRT-defibrillator (CRT-D) inserting and then measured its effects on these two groups. PATIENTS AND METHODS: Between 2010 and 2013, we conducted a prospective cohort study on 100 coronary artery disease patients where candidate for CABG. Then based on the receiving CRT-D, the patients were categorized in two groups; Group 1 ( n = 48, with CRT-D insertion before CABG) and Group 2 ( n = 52 without receiving CRT-D). Thereafter both of these groups were followed-up at 1-3 months after CABG for mortality, hospitalization, atrial fibrillation (AF), echocardiographic assessment, and New York Heart Association (NYHA) class level. RESULTS: The mean age of participants in Group 1 (48 male) and in Group 2 (52 male) was 58 +/- 13 and 57 +/- 12 respectively. Difference between Groups 1 and 2 in cases of mean left ventricular ejection fraction (LVEF) changes and NYHA class level was significant ( P > 0.05). Hospitalization ( P = 0.008), mortality rate ( P = 0.007), and AF were significantly different between these two groups. CONCLUSIONS: The results showed that the increase in LVEF and patient's improvement according to NYHA-class was significant in the first group, and readmission, mortality rate and AF was increased significantly in the second group. FAU - Karbasi Afshar, Reza AU - Karbasi Afshar R FAU - Ramezani Binabaj, Mahdi AU - Ramezani Binabaj M AD - Students' Research Committee, Baqiyatallah University of Medical Science, Tehran, Iran. FAU - Rezaee Zavareh, Mohammad Saeid AU - Rezaee Zavareh MS FAU - Saburi, Amin AU - Saburi A FAU - Ajudani, Reza AU - Ajudani R LA - eng PT - Journal Article PL - India TA - Ann Card Anaesth JT - Annals of cardiac anaesthesia JID - 9815987 SB - IM MH - Adult MH - Aged MH - Atrial Fibrillation/complications MH - Cardiac Resynchronization Therapy/*methods MH - Cardiopulmonary Bypass/*methods MH - Cohort Studies MH - *Defibrillators, Implantable MH - Electrocardiography MH - Female MH - *Heart Function Tests MH - Hospital Mortality MH - Hospitalization/statistics & numerical data MH - Humans MH - Male MH - Middle Aged MH - Postoperative Care MH - Prospective Studies MH - Stroke Volume MH - Ventricular Function, Left PMC - PMC4900314 COIS- Conflict of Interest: None declared. EDAT- 2015/01/09 06:00 MHDA- 2015/09/09 06:00 PMCR- 2015/01/01 CRDT- 2015/01/09 06:00 PHST- 2015/01/09 06:00 [entrez] PHST- 2015/01/09 06:00 [pubmed] PHST- 2015/09/09 06:00 [medline] PHST- 2015/01/01 00:00 [pmc-release] AID - AnnCardAnaesth_2015_18_1_34_148319 [pii] AID - ACA-18-34 [pii] AID - 10.4103/0971-9784.148319 [doi] PST - ppublish SO - Ann Card Anaesth. 2015 Jan-Mar;18(1):34-8. doi: 10.4103/0971-9784.148319.