PMID- 25572356
OWN - NLM
STAT- MEDLINE
DCOM- 20151113
LR  - 20220408
IS  - 1435-702X (Electronic)
IS  - 0721-832X (Linking)
VI  - 253
IP  - 5
DP  - 2015 May
TI  - The effects of ocular magnification on Spectralis spectral domain optical 
      coherence tomography scan length.
PG  - 733-8
LID - 10.1007/s00417-014-2915-9 [doi]
AB  - PURPOSE: The purpose of this study was to assess the effects of incorporating 
      individual ocular biometry measures of corneal curvature, refractive error, and 
      axial length on scan length obtained using Spectralis spectral domain optical 
      coherence tomography (SD-OCT). METHODS: Two SD-OCT scans were acquired for 50 
      eyes of 50 healthy participants, first using the Spectralis default keratometry 
      (K) setting followed by incorporating individual mean-K values. Resulting scan 
      lengths were compared to predicted scan lengths produced by image simulation 
      software, based on individual ocular biometry measures including axial length. 
      RESULTS: Axial length varied from 21.41 to 29.04 mm. Spectralis SD-OCT scan 
      lengths obtained with default-K ranged from 5.7 to 7.3 mm, and with mean-K from 
      5.6 to 7.6 mm. We report a stronger correlation of simulated scan lengths 
      incorporating the subject's mean-K value (rho = 0.926, P < 0.0005) compared to 
      Spectralis default settings (rho = 0.663, P < 0.0005). CONCLUSIONS: Ocular 
      magnification appears to be better accounted for when individual mean-K values 
      are incorporated into Spectralis SD-OCT scan acquisition versus using the 
      device's default-K setting. This must be considered when taking area measurements 
      and lateral measurements parallel to the retinal surface.
FAU - Ctori, Irene
AU  - Ctori I
AD  - Applied Vision Research Centre, The Henry Wellcome Laboratories for Vision 
      Sciences, City University London, Northampton Square, London, EC1V 0HB, UK, 
      Irene.Ctori.2@city.ac.uk.
FAU - Gruppetta, Stephen
AU  - Gruppetta S
FAU - Huntjens, Byki
AU  - Huntjens B
LA  - eng
PT  - Journal Article
DEP - 20150110
PL  - Germany
TA  - Graefes Arch Clin Exp Ophthalmol
JT  - Graefe's archive for clinical and experimental ophthalmology = Albrecht von 
      Graefes Archiv fur klinische und experimentelle Ophthalmologie
JID - 8205248
SB  - IM
MH  - Anatomy, Cross-Sectional
MH  - Axial Length, Eye/*pathology
MH  - Biometry
MH  - Cornea/*physiopathology
MH  - Female
MH  - Healthy Volunteers
MH  - Humans
MH  - Male
MH  - Refractive Errors/*physiopathology
MH  - Retina/*anatomy & histology
MH  - *Tomography, Optical Coherence
MH  - Young Adult
EDAT- 2015/01/13 06:00
MHDA- 2015/11/14 06:00
CRDT- 2015/01/10 06:00
PHST- 2014/07/17 00:00 [received]
PHST- 2014/12/22 00:00 [accepted]
PHST- 2014/12/16 00:00 [revised]
PHST- 2015/01/10 06:00 [entrez]
PHST- 2015/01/13 06:00 [pubmed]
PHST- 2015/11/14 06:00 [medline]
AID - 10.1007/s00417-014-2915-9 [doi]
PST - ppublish
SO  - Graefes Arch Clin Exp Ophthalmol. 2015 May;253(5):733-8. doi: 
      10.1007/s00417-014-2915-9. Epub 2015 Jan 10.