PMID- 25577008
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150813
LR  - 20150112
IS  - 1355-0306 (Print)
IS  - 1355-0306 (Linking)
VI  - 55
IP  - 1
DP  - 2015 Jan
TI  - Precursor discrimination of designer drug benzylpiperazine using delta13C and delta15N 
      stable isotopes.
PG  - 57-62
LID - S1355-0306(14)00110-5 [pii]
LID - 10.1016/j.scijus.2014.09.001 [doi]
AB  - Advances in analytical technology and emerging techniques have resulted in the 
      increased exploitation of chemical and isotopic profiling for source 
      linkage/discrimination of illicit drugs for forensic purposes. Although not 
      routinely used for illicit drug investigations, such information has been 
      obtained and its application demonstrated through the use of isotope ratio mass 
      spectrometry (IRMS). There is a solid platform of research available relating to 
      the isotopic analysis of methylenedioxymethamphetamine (MDMA) and methamphetamine 
      (MA), however with the recently flourishing designer drug market it was of 
      interest to examine the isotopic profiles of the popular 'party drug' 
      benzylpiperazine hydrochloride (BZP.HCl). A preliminary analysis of delta13C and delta15N 
      isotopic ratios in BZP.HCl products and corresponding synthetic intermediates 
      (piperazine.HCl) synthesized in-house from three different precursor suppliers 
      was conducted using IRMS. Analysis of the delta13C and delta15N isotopic data indicated 
      that discrimination and correct grouping of all the intermediates and some of the 
      product samples examined in this study were achievable.
CI  - Copyright (c) 2014 Forensic Science Society. Published by Elsevier Ireland Ltd. All 
      rights reserved.
FAU - Beckett, Nicola M
AU  - Beckett NM
AD  - School of Natural Sciences, Griffith University, Nathan campus, Queensland, 
      Australia; Institute for Glycomics, Griffith University, Gold Coast campus, 
      Queensland, Australia. Electronic address: n.beckett@griffith.edu.au.
FAU - Grice, Darren I
AU  - Grice DI
AD  - Institute for Glycomics, Griffith University, Gold Coast campus, Queensland, 
      Australia; School of Medical Science, Griffith University, Gold Coast campus, 
      Queensland, Australia. Electronic address: d.grice@griffith.edu.au.
FAU - Carter, James F
AU  - Carter JF
AD  - Queensland Health Forensic and Scientific Services, Coopers Plains, Queensland, 
      Australia. Electronic address: Jim_Carter@health.qld.gov.au.
FAU - Cresswell, Sarah L
AU  - Cresswell SL
AD  - School of Natural Sciences, Griffith University, Nathan campus, Queensland, 
      Australia. Electronic address: s.cresswell@griffith.edu.au.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20141005
PL  - England
TA  - Sci Justice
JT  - Science & justice : journal of the Forensic Science Society
JID - 9508563
OTO - NOTNLM
OT  - Benzylpiperazine
OT  - Designer drugs
OT  - IRMS
OT  - Isotopic profiling
OT  - Source discrimination
EDAT- 2015/01/13 06:00
MHDA- 2015/01/13 06:01
CRDT- 2015/01/12 06:00
PHST- 2014/01/14 00:00 [received]
PHST- 2014/08/06 00:00 [revised]
PHST- 2014/09/01 00:00 [accepted]
PHST- 2015/01/12 06:00 [entrez]
PHST- 2015/01/13 06:00 [pubmed]
PHST- 2015/01/13 06:01 [medline]
AID - S1355-0306(14)00110-5 [pii]
AID - 10.1016/j.scijus.2014.09.001 [doi]
PST - ppublish
SO  - Sci Justice. 2015 Jan;55(1):57-62. doi: 10.1016/j.scijus.2014.09.001. Epub 2014 
      Oct 5.