PMID- 25579005
OWN - NLM
STAT- MEDLINE
DCOM- 20150329
LR  - 20150112
IS  - 1531-5053 (Electronic)
IS  - 0278-2391 (Linking)
VI  - 73
IP  - 2
DP  - 2015 Feb
TI  - Management of tooth extraction in a patient with a rare bleeding disorder 
      associated with Hermansky-Pudlak syndrome: a case report.
PG  - 219-23
LID - S0278-2391(14)01409-8 [pii]
LID - 10.1016/j.joms.2014.08.037 [doi]
AB  - PURPOSE: This report describes the case of a 27-year-old man who had been 
      diagnosed with Hermansky-Pudlak syndrome shortly after birth. Because the patient 
      had a major bleeding disorder associated with his syndrome, local and systemic 
      hemostatic protection recommendations had to be considered before tooth 
      extraction. MATERIALS AND METHODS: Synthetic vasopressin (1-deamino-8-d-arginine 
      vasopressin [DDAVP]) was transfused intravenously before surgery. During surgery 
      the patient was transfused with 1 U of human leukocyte antigen (HLA)-matched 
      apheresis platelets. A hemostatic packing of Avitene and Gelfoam was adapted to 
      the extraction site. RESULTS: Treatment with DDAVP, HLA-matched platelets, and 
      local application of a packing with Avitene and Gelfoam resulted in sustained 
      hemostasis and an excellent healing response. CONCLUSION: Surgical and routine 
      extractions appear to be safe procedures in patients with Hermansky-Pudlak 
      syndrome when appropriate local and systemic hemostatic measures are used.
CI  - Copyright (c) 2015 American Association of Oral and Maxillofacial Surgeons. 
      Published by Elsevier Inc. All rights reserved.
FAU - Minkin, Patton
AU  - Minkin P
AD  - Resident, Department of Oral and Maxillofacial Surgery, Mt Sinai-St Luke's/Mt 
      Sinai-Roosevelt Hospitals, New York, NY. Electronic address: pminkin@chpnet.org.
FAU - Bertetti, Richard
AU  - Bertetti R
AD  - Chief Resident, Department of Oral and Maxillofacial Surgery, Mt Sinai-St 
      Luke's/Mt Sinai-Roosevelt Hospitals, New York, NY.
FAU - Lindsey, Sean
AU  - Lindsey S
AD  - Junior Resident, Department of Oral and Maxillofacial Surgery, Mt Sinai-St 
      Luke's/Mt Sinai-Roosevelt Hospitals, New York, NY.
FAU - Bovino, Brian
AU  - Bovino B
AD  - Residency Program Director, Department of Oral and Maxillofacial Surgery, Mt 
      Sinai-St Luke's/Mt Sinai-Roosevelt Hospitals, New York, NY.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20140916
PL  - United States
TA  - J Oral Maxillofac Surg
JT  - Journal of oral and maxillofacial surgery : official journal of the American 
      Association of Oral and Maxillofacial Surgeons
JID - 8206428
SB  - IM
MH  - Adult
MH  - Blood Coagulation Disorders/*physiopathology
MH  - Hermanski-Pudlak Syndrome/*physiopathology
MH  - Humans
MH  - Male
MH  - *Tooth Extraction
EDAT- 2015/01/13 06:00
MHDA- 2015/03/31 06:00
CRDT- 2015/01/13 06:00
PHST- 2014/04/28 00:00 [received]
PHST- 2014/08/23 00:00 [revised]
PHST- 2014/08/30 00:00 [accepted]
PHST- 2015/01/13 06:00 [entrez]
PHST- 2015/01/13 06:00 [pubmed]
PHST- 2015/03/31 06:00 [medline]
AID - S0278-2391(14)01409-8 [pii]
AID - 10.1016/j.joms.2014.08.037 [doi]
PST - ppublish
SO  - J Oral Maxillofac Surg. 2015 Feb;73(2):219-23. doi: 10.1016/j.joms.2014.08.037. 
      Epub 2014 Sep 16.