PMID- 25579723 OWN - NLM STAT- MEDLINE DCOM- 20150311 LR - 20191113 IS - 1319-2442 (Print) IS - 1319-2442 (Linking) VI - 26 IP - 1 DP - 2015 Jan TI - Polyomavirus-associated nephropathy in renal and simultaneous pancreas-kidney transplant recipients: report of three cases. PG - 94-7 AB - Infection with polyomavirus (BK virus) is the cause of renal graft losses in more than 50% of the infected cases. There should be a high index of suspicion about this disease, although the incidence is only between 2% and 5% as the future of renal graft depends on the early and appropriate management of the same. Herein, we describe three clinical cases: Two were those of kidney transplant and the third, a combined kidney-pancreas transplant. In these cases, by reducing immunosuppression and, in one case, replacing the calcineurin inhibitor by MTOR (mammalian target of rapamycin) in addition, we were able to preserve of the normal function of the transplanted organs. FAU - Cadavid, Dahyana AU - Cadavid D AD - Division of Internal Medicine, Fundacion Valle del Lili, Cali, Universidad CES, Medellin, Colombia. FAU - Mesa, Liliana AU - Mesa L FAU - Schweineberg, Johanna AU - Schweineberg J FAU - Posada, Juan G AU - Posada JG LA - eng PT - Case Reports PT - Journal Article PL - Saudi Arabia TA - Saudi J Kidney Dis Transpl JT - Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia JID - 9436968 RN - 0 (Immunosuppressive Agents) SB - IM MH - Adult MH - *BK Virus MH - Female MH - Graft Survival MH - Humans MH - Immunosuppressive Agents/administration & dosage/*adverse effects MH - Kidney Cortex Necrosis/*virology MH - Kidney Transplantation/*adverse effects MH - Male MH - Middle Aged MH - Pancreas Transplantation/adverse effects MH - Polyomavirus Infections/*complications MH - Tumor Virus Infections/*complications EDAT- 2015/01/13 06:00 MHDA- 2015/03/12 06:00 CRDT- 2015/01/13 06:00 PHST- 2015/01/13 06:00 [entrez] PHST- 2015/01/13 06:00 [pubmed] PHST- 2015/03/12 06:00 [medline] AID - SaudiJKidneyDisTranspl_2015_26_1_94_148750 [pii] AID - 10.4103/1319-2442.148750 [doi] PST - ppublish SO - Saudi J Kidney Dis Transpl. 2015 Jan;26(1):94-7. doi: 10.4103/1319-2442.148750.