PMID- 2558155
OWN - NLM
STAT- MEDLINE
DCOM- 19900222
LR  - 20191210
IS  - 0022-1317 (Print)
IS  - 0022-1317 (Linking)
VI  - 70 ( Pt 12)
DP  - 1989 Dec
TI  - Presence of antibody to human herpesvirus 6 in monkeys.
PG  - 3171-6
AB  - A serological survey of monkeys was conducted to determine the prevalence of 
      antibody to human herpesvirus 6 (HHV-6). Two-hundred and fifteen sera from 10 
      species of monkeys were examined by an immunofluorescent antibody (IF) assay. The 
      antibody was found in monkeys from eight of the 10 species examined, but was not 
      detected in silvered lutongs or cotton-top tamarins. The prevalence of antibody 
      was highest in squirrel monkeys. Sera with high antibody titres were examined 
      further by Western blot analysis and the neutralizing antibody test and the 
      antibody levels were compared with that from a patient with exanthem subitum. On 
      Western blotting, monkey and human sera that were antibody-positive to HHV-6 
      antigen gave similar reactions with antigen components of almost the same Mr. 
      Furthermore, sera that were antibody-positive by the IF test were also positive 
      by the neutralizing antibody test and their titres in the two tests were 
      comparable. These results suggest the existence of HHV-6 or an HHV-6-related 
      virus in monkeys.
FAU - Higashi, K
AU  - Higashi K
AD  - Department of Virology, Osaka University, Japan.
FAU - Asada, H
AU  - Asada H
FAU - Kurata, T
AU  - Kurata T
FAU - Ishikawa, K
AU  - Ishikawa K
FAU - Hayami, M
AU  - Hayami M
FAU - Spriatna, Y
AU  - Spriatna Y
FAU - Sutarman
AU  - Sutarman
FAU - Yamanishi, K
AU  - Yamanishi K
LA  - eng
PT  - Journal Article
PL  - England
TA  - J Gen Virol
JT  - The Journal of general virology
JID - 0077340
RN  - 0 (Antibodies, Viral)
SB  - IM
MH  - Animals
MH  - Antibodies, Viral/*analysis
MH  - Blotting, Western
MH  - Cercopithecidae
MH  - Chlorocebus aethiops
MH  - Cross Reactions
MH  - Fluorescent Antibody Technique
MH  - *Haplorhini
MH  - Herpesviridae Infections/epidemiology/*veterinary
MH  - Herpesvirus 6, Human/*immunology
MH  - Humans
MH  - Hylobates
MH  - Macaca
MH  - Macaca fascicularis
MH  - Macaca nemestrina
MH  - Monkey Diseases/*epidemiology
MH  - Neutralization Tests
MH  - Pan troglodytes
MH  - Pongo pygmaeus
MH  - Prevalence
MH  - Saguinus
MH  - Saimiri
EDAT- 1989/12/01 00:00
MHDA- 1989/12/01 00:01
CRDT- 1989/12/01 00:00
PHST- 1989/12/01 00:00 [pubmed]
PHST- 1989/12/01 00:01 [medline]
PHST- 1989/12/01 00:00 [entrez]
AID - 10.1099/0022-1317-70-12-3171 [doi]
PST - ppublish
SO  - J Gen Virol. 1989 Dec;70 ( Pt 12):3171-6. doi: 10.1099/0022-1317-70-12-3171.