PMID- 25583540
OWN - NLM
STAT- MEDLINE
DCOM- 20160325
LR  - 20220409
IS  - 1939-0041 (Electronic)
IS  - 1939-0041 (Linking)
VI  - 7
IP  - 4
DP  - 2015 Jul-Aug
TI  - Advances in the synthesis and application of nanoparticles for drug delivery.
PG  - 494-508
LID - 10.1002/wnan.1325 [doi]
AB  - The continuous development of drug delivery systems (DDSs) has been extensively 
      researched by the need to maximize therapeutic efficacy while minimizing 
      undesirable side effects. Nanoparticle technology was recently shown to hold 
      great promise for drug delivery applications in nanomedicine due to its 
      beneficial properties, such as better encapsulation, bioavailability, control 
      release, and lower toxic effect. Despite the great progress in nanomedicine, 
      there remain many limitations for clinical application. To overcome these 
      limitations, advanced nanoparticles for drug delivery have been developed to 
      enable the spatially and temporally controlled release of drugs in response to 
      specific stimuli at disease sites. Furthermore, the controlled self-assembly of 
      organic and inorganic materials may enable their use in theranostic applications. 
      This review presents an overview of a recent advanced nanoparticulate system that 
      can be used as a potential drug delivery carrier and focuses on the potential 
      applications of nanoparticles in various biomedical fields for human health care.
CI  - (c) 2015 Wiley Periodicals, Inc.
FAU - Park, Wooram
AU  - Park W
AD  - Department of Biotechnology, The Catholic University of Korea, Bucheon-si, Korea.
FAU - Na, Kun
AU  - Na K
AD  - Department of Biotechnology, The Catholic University of Korea, Bucheon-si, Korea.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Review
DEP - 20150113
PL  - United States
TA  - Wiley Interdiscip Rev Nanomed Nanobiotechnol
JT  - Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
JID - 101508311
RN  - 0 (Antineoplastic Agents)
RN  - 0 (Liposomes)
SB  - IM
MH  - Animals
MH  - Antineoplastic Agents/pharmacology
MH  - Drug Delivery Systems/*methods
MH  - Humans
MH  - Liposomes/chemistry
MH  - Nanoparticles/*chemistry
MH  - Photochemotherapy
MH  - Theranostic Nanomedicine
EDAT- 2015/01/15 06:00
MHDA- 2016/03/26 06:00
CRDT- 2015/01/14 06:00
PHST- 2014/07/30 00:00 [received]
PHST- 2014/11/08 00:00 [accepted]
PHST- 2015/01/14 06:00 [entrez]
PHST- 2015/01/15 06:00 [pubmed]
PHST- 2016/03/26 06:00 [medline]
AID - 10.1002/wnan.1325 [doi]
PST - ppublish
SO  - Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2015 Jul-Aug;7(4):494-508. doi: 
      10.1002/wnan.1325. Epub 2015 Jan 13.