PMID- 25585155
OWN - NLM
STAT- MEDLINE
DCOM- 20150826
LR  - 20150216
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 511
DP  - 2015 Apr 1
TI  - Serum levels of persistent organic pollutants and predictors of exposure in 
      Tunisian women.
PG  - 530-4
LID - S0048-9697(14)01804-X [pii]
LID - 10.1016/j.scitotenv.2014.12.093 [doi]
AB  - INTRODUCTION: In spite of the international consensus on the human health risks 
      associated with exposure to persistent organic pollutants (POPs), the Tunisian 
      population is suspected to have been inadvertently exposed to POPs over the last 
      decades. OBJECTIVES: The aim of this study was to evaluate POP concentrations in 
      the serum of a subset of 54 Tunisian women and to identify some socio-demographic 
      and dietary predictors of exposure to POPs. RESULTS: Of the ten POPs analyzed, 
      three polychlorinated biphenyl (PCB) congeners (-138, -153 and -180), and two 
      organochlorine pesticides (OCPs), HCB and p,p'-DDE, showed frequencies ranging 
      from 98 to 100%. Serum median concentrations of PCB congeners (-138, -153 
      PCB-180) were 26.08, 119.1 and 29.84 ng/g lipid, respectively, and median 
      concentrations of HCB and p,p'-DDE were 19.98 and 127.59 ng/g lipid, 
      respectively. Age was positively correlated with serum levels of selected POPs. 
      Women living in northern Tunisia showed higher serum levels of all PCBs. Working 
      outside home and cereal consumption were positively associated to serum levels of 
      p,p'-DDE. The duration of the lactation was also related to lower serum levels of 
      p,p'-DDE and HCB. CONCLUSION: The levels of exposure to POPs found warrant a 
      biomonitoring program in order to identify routes of exposure and population 
      groups at higher risk. This program will help to establish prevention policies 
      and to determine the association between exposure to POPs and chronic diseases.
CI  - Copyright (c) 2014 Elsevier B.V. All rights reserved.
FAU - Artacho-Cordon, F
AU  - Artacho-Cordon F
AD  - Radiology and Physical Medicine Department, University of Granada, Granada, 
      Spain; Instituto de Investigacion Biosanitaria IBS.Granada, Hospitales 
      Universitarios de Granada/Universidad de Granada, Granada, Spain. Electronic 
      address: fartacho@ugr.es.
FAU - Belhassen, H
AU  - Belhassen H
AD  - Laboratory of Toxicology and Environment (LR12SP07), Center of Urgent Medical 
      Assistance of Tunis, Tunis, Tunisia.
FAU - Arrebola, J P
AU  - Arrebola JP
AD  - Instituto de Investigacion Biosanitaria IBS.Granada, Hospitales Universitarios de 
      Granada/Universidad de Granada, Granada, Spain; CIBER en Epidemiologia y Salud 
      Publica (CIBERESP), Spain; Radiation Oncology Department, Virgen de las Nieves 
      University Hospital, Granada, Spain.
FAU - Ghali, R
AU  - Ghali R
AD  - Laboratory of Toxicology and Environment (LR12SP07), Center of Urgent Medical 
      Assistance of Tunis, Tunis, Tunisia.
FAU - Amira, D
AU  - Amira D
AD  - Laboratory of Toxicology and Environment (LR12SP07), Center of Urgent Medical 
      Assistance of Tunis, Tunis, Tunisia.
FAU - Jimenez-Diaz, I
AU  - Jimenez-Diaz I
AD  - Instituto de Investigacion Biosanitaria IBS.Granada, Hospitales Universitarios de 
      Granada/Universidad de Granada, Granada, Spain.
FAU - Perez-Lobato, R
AU  - Perez-Lobato R
AD  - Instituto de Investigacion Biosanitaria IBS.Granada, Hospitales Universitarios de 
      Granada/Universidad de Granada, Granada, Spain.
FAU - H, Boussen
AU  - H B
AD  - Cancer Center of Ariana, Ariana, Tunisia.
FAU - A, Hedili
AU  - A H
AD  - Laboratory of Toxicology and Environment (LR12SP07), Center of Urgent Medical 
      Assistance of Tunis, Tunis, Tunisia.
FAU - Olea, N
AU  - Olea N
AD  - Radiology and Physical Medicine Department, University of Granada, Granada, 
      Spain; Instituto de Investigacion Biosanitaria IBS.Granada, Hospitales 
      Universitarios de Granada/Universidad de Granada, Granada, Spain; CIBER en 
      Epidemiologia y Salud Publica (CIBERESP), Spain.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150109
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Environmental Pollutants)
RN  - 0 (Hydrocarbons, Chlorinated)
RN  - 0 (Pesticides)
RN  - 4M7FS82U08 (Dichlorodiphenyl Dichloroethylene)
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
SB  - IM
MH  - Adult
MH  - Dichlorodiphenyl Dichloroethylene/blood
MH  - Environmental Exposure/*statistics & numerical data
MH  - Environmental Pollutants/*blood
MH  - Female
MH  - Humans
MH  - Hydrocarbons, Chlorinated/blood
MH  - Pesticides/blood
MH  - Polychlorinated Biphenyls/blood
MH  - Tunisia
MH  - Young Adult
OTO - NOTNLM
OT  - Exposure predictors
OT  - Organochlorine pesticides
OT  - Persistent organic pollutant
OT  - Polychlorinated biphenyls
OT  - Serum
OT  - Tunisia
EDAT- 2015/01/15 06:00
MHDA- 2015/08/27 06:00
CRDT- 2015/01/14 06:00
PHST- 2014/10/09 00:00 [received]
PHST- 2014/12/04 00:00 [revised]
PHST- 2014/12/28 00:00 [accepted]
PHST- 2015/01/14 06:00 [entrez]
PHST- 2015/01/15 06:00 [pubmed]
PHST- 2015/08/27 06:00 [medline]
AID - S0048-9697(14)01804-X [pii]
AID - 10.1016/j.scitotenv.2014.12.093 [doi]
PST - ppublish
SO  - Sci Total Environ. 2015 Apr 1;511:530-4. doi: 10.1016/j.scitotenv.2014.12.093. 
      Epub 2015 Jan 9.