PMID- 25598629 OWN - NLM STAT- PubMed-not-MEDLINE DCOM- 20150119 LR - 20220311 IS - 0976-4836 (Print) IS - 0974-8490 (Electronic) IS - 0974-8490 (Linking) VI - 7 IP - 1 DP - 2015 Jan-Mar TI - Chemical Constituents from the Leaves of Euphorbia ammak Growing in Saudi Arabia. PG - 14-7 LID - 10.4103/0974-8490.147136 [doi] AB - Investigation of the chloroform extract of Euphorbia ammak leaves led to the isolation of three compounds: euphol (1), alpha-glutinol (2) and stigmasterol (3) Their structures were elucidated by 1D and 2D NMR, as well as by comparison with the reported data. Compounds 1-3 exhibited cytotoxicity in vitro against human cervical adenocarcinoma (Hela), among which, compound 1 showed the best activity. FAU - Abdel-Sattar, Essam AU - Abdel-Sattar E AD - Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt. FAU - Abou-Hussein, Dina AU - Abou-Hussein D AD - Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Cairo 11562, Egypt ; Department of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, Jeddah, 21589, Saudi Arabia. FAU - Petereit, Frank AU - Petereit F AD - University of Munster, Institute of Pharmaceutical Biology and Phytochemistry, Hittorfstrasse 56, D-48149 Munster, Germany. LA - eng PT - Journal Article PL - India TA - Pharmacognosy Res JT - Pharmacognosy research JID - 101558769 PMC - PMC4285643 OTO - NOTNLM OT - Cervical adenocarcinoma OT - Euphorbia ammak OT - euphol COIS- Conflict of Interest: None declared. EDAT- 2015/01/20 06:00 MHDA- 2015/01/20 06:01 PMCR- 2015/01/01 CRDT- 2015/01/20 06:00 PHST- 2014/04/29 00:00 [received] PHST- 2014/06/09 00:00 [revised] PHST- 2014/12/17 00:00 [accepted] PHST- 2015/01/20 06:00 [entrez] PHST- 2015/01/20 06:00 [pubmed] PHST- 2015/01/20 06:01 [medline] PHST- 2015/01/01 00:00 [pmc-release] AID - PR-7-14 [pii] AID - 10.4103/0974-8490.147136 [doi] PST - ppublish SO - Pharmacognosy Res. 2015 Jan-Mar;7(1):14-7. doi: 10.4103/0974-8490.147136.