PMID- 25601015 OWN - NLM STAT- MEDLINE DCOM- 20171030 LR - 20171126 IS - 1751-7893 (Electronic) IS - 1751-7885 (Linking) VI - 10 IP - 6 DP - 2016 Dec TI - Gender differences in patients with first-episode psychosis in the Singapore Early Psychosis Intervention Programme. PG - 528-534 LID - 10.1111/eip.12208 [doi] AB - AIMS: This study aimed to identify the gender differences among multi-ethnic, Asian patients with first-episode psychosis attending the Early Psychosis Intervention Programme (EPIP) in Singapore. METHODS: Data for this study were derived from 533 (258 female, 275 male) patients aged 16-41 years old in the EPIP database. Socio-demographic data, Positive and Negative Syndrome Scale for schizophrenia (PANSS) and Global Assessment of Functioning (GAF) scores at baseline, 3 months, 6 months and 1 year were obtained. RESULTS: Significant gender differences were identified in terms of age, marital status, referral source, PANSS scores, GAF scores, remission and recovery over 1 year in the cohort. At service entry, female participants were older, more likely to be married and more likely to be referred from general practitioner/polyclinics (P < 0.0001). They showed better improvement over 1 year in PANSS positive, PANSS total, GAF disability and GAF total scores. CONCLUSIONS: Overall, female participants in this sample show better improvement than male participants. They showed a better course of illness over 1 year with one-third (33.3%) of female participants achieving recovery compared with approximately a quarter (23.6%) of male participants. CI - (c) 2015 Wiley Publishing Asia Pty Ltd. FAU - Pang, Shirlene AU - Pang S AD - Research Division, Institute of Mental Health, Singapore. shirlene_pang@imh.com.sg. FAU - Subramaniam, Mythily AU - Subramaniam M AD - Research Division, Institute of Mental Health, Singapore. FAU - Abdin, Edimansyah AU - Abdin E AD - Research Division, Institute of Mental Health, Singapore. FAU - Poon, Lye Yin AU - Poon LY AD - Department of Early Psychosis Intervention, Institute of Mental Health, Singapore. FAU - Chong, Siow Ann AU - Chong SA AD - Research Division, Institute of Mental Health, Singapore. FAU - Verma, Swapna AU - Verma S AD - Department of Early Psychosis Intervention, Institute of Mental Health, Singapore. LA - eng PT - Journal Article DEP - 20150120 PL - Australia TA - Early Interv Psychiatry JT - Early intervention in psychiatry JID - 101320027 SB - IM MH - Adolescent MH - Adult MH - Female MH - Humans MH - Male MH - Prognosis MH - Psychiatric Status Rating Scales MH - Psychotic Disorders/*diagnosis MH - *Sex Characteristics MH - Singapore MH - Young Adult OTO - NOTNLM OT - early intervention OT - early psychosis OT - first-episode psychosis OT - gender difference OT - remission EDAT- 2016/10/21 06:00 MHDA- 2017/10/31 06:00 CRDT- 2015/01/21 06:00 PHST- 2014/08/20 00:00 [received] PHST- 2014/11/09 00:00 [accepted] PHST- 2016/10/21 06:00 [pubmed] PHST- 2017/10/31 06:00 [medline] PHST- 2015/01/21 06:00 [entrez] AID - 10.1111/eip.12208 [doi] PST - ppublish SO - Early Interv Psychiatry. 2016 Dec;10(6):528-534. doi: 10.1111/eip.12208. Epub 2015 Jan 20.