PMID- 25609549 OWN - NLM STAT- MEDLINE DCOM- 20160609 LR - 20221207 IS - 2326-3660 (Electronic) IS - 0091-3847 (Linking) VI - 43 IP - 1 DP - 2015 Feb TI - A randomized study of raisins versus alternative snacks on glycemic control and other cardiovascular risk factors in patients with type 2 diabetes mellitus. PG - 37-43 LID - 10.1080/00913847.2015.998410 [doi] AB - Just as the type and duration of physical activity can have variable effects on the glucose levels and other cardiometabolic parameters among patients with type 2 diabetes mellitus (T2DM), so can the types of foods have variable effects as well. This 12-week randomized study of 51 study participants evaluated the impact of routine consumption of dark raisins versus alternative processed snacks on glucose levels and other cardiovascular risk factors among patients with type T2DM. In this study, compared to alternative processed snacks, those who consumed raisins had a significant 23% reduction in postprandial glucose levels (P = 0.024). Also compared to snacks, those who consumed raisins had a 19% reduction in fasting glucose and 0.12% reduction in hemoglobin A1c, although these latter findings did not achieve statistical significance. Regarding blood pressure, compared to alternative processed snacks, those who consumed raisins had a significant 8.7 mmHg reduction in systolic blood pressure (P = 0.035) (7.5% [P = 0.031]) but did not experience a significant reduction in diastolic blood pressure. Compared to alternative processed snacks, those who consumed raisins did not have a significant improvement in body weight, body mass index, waist circumference, fasting insulin, homeostatic model assessment of insulin resistance, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol (HDL), triglyceride, or non-HDL cholesterol levels. Overall, these data support raisins as a healthy alternative compare to processed snacks in patients with T2DM. FAU - Bays, Harold AU - Bays H AD - Louisville Metabolic and Atherosclerotic Research Center , 3288 Illinois Ave, Louisville, KY 40213 , USA. FAU - Weiter, Kathy AU - Weiter K FAU - Anderson, James AU - Anderson J LA - eng PT - Comparative Study PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't DEP - 20150122 PL - England TA - Phys Sportsmed JT - The Physician and sportsmedicine JID - 0427461 RN - 0 (Blood Glucose) RN - 0 (Glycated Hemoglobin A) RN - 0 (Lipids) SB - IM MH - Blood Glucose/*metabolism MH - Blood Pressure/*drug effects MH - Body Mass Index MH - Body Weight MH - *Cardiovascular Diseases/etiology/prevention & control MH - Desiccation MH - Diabetes Mellitus, Type 2/blood/*diet therapy MH - Female MH - Food Handling MH - *Fruit MH - Glycated Hemoglobin/metabolism MH - Humans MH - Insulin Resistance MH - Lipids/blood MH - Male MH - Middle Aged MH - Risk Factors MH - *Snacks MH - *Vitis OTO - NOTNLM OT - Adiposopathy OT - blood pressure OT - diabetes mellitus OT - dry fruit OT - obesity OT - raisins EDAT- 2015/01/23 06:00 MHDA- 2016/06/10 06:00 CRDT- 2015/01/23 06:00 PHST- 2015/01/23 06:00 [entrez] PHST- 2015/01/23 06:00 [pubmed] PHST- 2016/06/10 06:00 [medline] AID - 10.1080/00913847.2015.998410 [doi] PST - ppublish SO - Phys Sportsmed. 2015 Feb;43(1):37-43. doi: 10.1080/00913847.2015.998410. Epub 2015 Jan 22.