PMID- 25612842
OWN - NLM
STAT- MEDLINE
DCOM- 20150910
LR  - 20210331
IS  - 1421-9832 (Electronic)
IS  - 1018-8665 (Linking)
VI  - 230
IP  - 1
DP  - 2015
TI  - Persistent pityriasis rosea: an unusual form of pityriasis rosea with persistent 
      active HHV-6 and HHV-7 infection.
PG  - 23-6
LID - 10.1159/000368352 [doi]
AB  - Pityriasis rosea (PR) is an acute, self-limiting exanthematous disease, 
      associated with the reactivation of the human herpesvirus 6 (HHV-6) and/or human 
      herpesvirus 7 (HHV-7) that usually lasts 6-8 weeks. We studied, from a clinical 
      and virological point of view, 12 patients in whom the features of PR lasted 
      longer than 12 weeks, defining this form of the disease as persistent PR (PPR). 
      As in typical PR, in most of the PPR patients the disease begins with a herald 
      patch, but compared to typical PR, systemic symptoms and oral lesions are more 
      common. Moreover, in PPR we found a persistent reactivation of HHV-6 and/or HHV-7 
      with higher viral loads than in typical PR, accounting for the unusual 
      persistence of the illness, the more frequent and severer systemic symptoms and 
      the oral lesions. In conclusion, we describe an unusual persistent form of PR, 
      whose prevalence has probably been underestimated so far and which should be 
      added to the other variants of PR.
CI  - (c) 2015 S. Karger AG, Basel.
FAU - Drago, Francesco
AU  - Drago F
AD  - Department of Dermatology, DISSAL, IRCCS AOU San Martino - IST, Genoa, Italy.
FAU - Broccolo, Francesco
AU  - Broccolo F
FAU - Ciccarese, Giulia
AU  - Ciccarese G
FAU - Rebora, Alfredo
AU  - Rebora A
FAU - Parodi, Aurora
AU  - Parodi A
LA  - eng
PT  - Journal Article
DEP - 20150116
PL  - Switzerland
TA  - Dermatology
JT  - Dermatology (Basel, Switzerland)
JID - 9203244
SB  - IM
MH  - Adult
MH  - Female
MH  - Herpesviridae Infections/complications/*immunology/virology
MH  - Herpesvirus 6, Human/*immunology
MH  - Herpesvirus 7, Human/*immunology
MH  - Humans
MH  - Male
MH  - Pityriasis Rosea/complications/immunology/*virology
MH  - Viral Load
MH  - Young Adult
EDAT- 2015/01/24 06:00
MHDA- 2015/09/12 06:00
CRDT- 2015/01/24 06:00
PHST- 2014/08/06 00:00 [received]
PHST- 2014/09/06 00:00 [accepted]
PHST- 2015/01/24 06:00 [entrez]
PHST- 2015/01/24 06:00 [pubmed]
PHST- 2015/09/12 06:00 [medline]
AID - 000368352 [pii]
AID - 10.1159/000368352 [doi]
PST - ppublish
SO  - Dermatology. 2015;230(1):23-6. doi: 10.1159/000368352. Epub 2015 Jan 16.