PMID- 25613671
OWN - NLM
STAT- MEDLINE
DCOM- 20150910
LR  - 20220321
IS  - 1421-9832 (Electronic)
IS  - 1018-8665 (Linking)
VI  - 230
IP  - 1
DP  - 2015
TI  - Determining the minimal clinically important difference and responsiveness of the 
      Dermatology Life Quality Index (DLQI): further data.
PG  - 27-33
LID - 10.1159/000365390 [doi]
AB  - AIMS: To determine the minimal clinically important difference (MCID) of the 
      Dermatology Life Quality Index (DLQI) and its responsiveness to change in 
      inflammatory skin diseases. METHODS: A longitudinal study: at stage 1, patients 
      completed the DLQI and a disease severity global question; at stage 2, a global 
      rating of change in quality of life (QoL; Global Rating of Change Questionnaire, 
      GRCQ) was added and used as an anchor to measure the MCID of the DLQI. RESULTS: 
      192 patients completed stage 1 and 107 completed stage 2. The mean DLQI score at 
      stage 1 was 9.8 and 7.4 at stage 2 with a mean change of 2.4 (p < 0.0001). 31 
      patients experienced a 'small change' in their QoL (+/-3 and +/-2) on the GRCQ. The 
      mean corresponding change in DLQI scores was 3.3, which is regarded as the 
      approximate MCID. CONCLUSIONS: Previous estimates of the MCID of the DLQI have 
      varied from 3 to 5. Although this study demonstrated a MCID of 3.3, we recommend 
      that the MCID in inflammatory skin diseases should be 4.
CI  - (c) 2015 S. Karger AG, Basel.
FAU - Basra, M K A
AU  - Basra MK
AD  - Department of Dermatology, Derriford Hospital, Plymouth, UK.
FAU - Salek, M S
AU  - Salek MS
FAU - Camilleri, L
AU  - Camilleri L
FAU - Sturkey, R
AU  - Sturkey R
FAU - Finlay, A Y
AU  - Finlay AY
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150120
PL  - Switzerland
TA  - Dermatology
JT  - Dermatology (Basel, Switzerland)
JID - 9203244
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Dermatology
MH  - Female
MH  - Humans
MH  - Longitudinal Studies
MH  - Male
MH  - Middle Aged
MH  - *Quality of Life
MH  - *Skin Diseases
MH  - Surveys and Questionnaires
MH  - Young Adult
EDAT- 2015/01/24 06:00
MHDA- 2015/09/12 06:00
CRDT- 2015/01/24 06:00
PHST- 2014/03/02 00:00 [received]
PHST- 2014/06/19 00:00 [accepted]
PHST- 2015/01/24 06:00 [entrez]
PHST- 2015/01/24 06:00 [pubmed]
PHST- 2015/09/12 06:00 [medline]
AID - 000365390 [pii]
AID - 10.1159/000365390 [doi]
PST - ppublish
SO  - Dermatology. 2015;230(1):27-33. doi: 10.1159/000365390. Epub 2015 Jan 20.