PMID- 25620255 OWN - NLM STAT- MEDLINE DCOM- 20150519 LR - 20181202 IS - 0253-3758 (Print) IS - 0253-3758 (Linking) VI - 42 IP - 11 DP - 2014 Nov TI - [Diagnostic value of cardiac magnetic resonance in patients with acute viral myocarditis]. PG - 927-31 AB - OBJECTIVE: To assess the diagnostic value of cardiac magnetic resonance (CMR) in patients with acute viral myocarditis. METHODS: Thirty patients with suspected acute viral myocarditis admitted in first people's hospital of Shunde from June 2011 to June 2013 were included in this prospective study. The diagnostic sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of acute viral myocarditis were evaluated by clinical diagnosis. Diagnostic value among different scan methods and Lake Louise criteria were compared. RESULTS: Acute viral myocarditis was diagnosed in 63.33% (19/30) patients.Values for sensitivity, specificity, PPV, NPV, and diagnostic accuracy within the overall cohort were 57.89%, 72.73%, 78.57%, 50.00%, 63.33%, respectively by edema imaging (ER).Values for sensitivity, specificity, PPV, NPV, and diagnostic accuracy within the overall cohort were 78.95%, 63.64%, 78.95%, 63.64%, 73.33%, respectively using global relative enhancement (gRE).Values for sensitivity, specificity, PPV, NPV, and diagnostic accuracy within the overall cohort were 78.95%, 54.55%, 75.00%, 60.00%, 70.00%, respectively using late gadolinium enhancement (LGE) criteria.Values for sensitivity, specificity, PPV, NPV, and diagnostic accuracy within the overall cohort were 84.21%, 81.82%, 88.89%, 75.00%, 83.33% using Lake Louise criteria. The sensitivity, specificity, PPV, NPV, and diagnostic accuracy using Lake Louise criteria were significantly higher than using ER, gRE, LGE alone(all P < 0.05).Specificity was higher using ER than using gRE and LGE (both P < 0.05). The sensitivity, NPV, and diagnostic accuracy were significantly higher using gRE than using ER (all P < 0.05) and was similar as using LGE (all P > 0.05). CONCLUSION: Cardiac magnetic resonance is an excellent imaging modality for the diagnosis of acute viral myocarditis. FAU - Ouyang, Haichun AU - Ouyang H AD - Department of Cardiology, First People's Hospital of Shunde, Foshan 528300, China. FAU - Chen, Haixiong AU - Chen H FAU - Hu, Yunzhao AU - Hu Y FAU - Wu, Yanxian AU - Wu Y AD - Email: wuyanxian200@sohu.com. FAU - Li, Wensheng AU - Li W FAU - Chen, Yuying AU - Chen Y FAU - Cen, Yujian AU - Cen Y LA - chi PT - Journal Article PL - China TA - Zhonghua Xin Xue Guan Bing Za Zhi JT - Zhonghua xin xue guan bing za zhi JID - 7910682 RN - 0 (Contrast Media) RN - AU0V1LM3JT (Gadolinium) SB - IM MH - Acute Disease MH - Contrast Media MH - Gadolinium MH - Heart MH - Humans MH - *Magnetic Resonance Spectroscopy MH - Myocarditis/*diagnosis/*virology MH - Predictive Value of Tests MH - Prospective Studies MH - Sensitivity and Specificity EDAT- 2015/01/27 06:00 MHDA- 2015/05/20 06:00 CRDT- 2015/01/27 06:00 PHST- 2015/01/27 06:00 [entrez] PHST- 2015/01/27 06:00 [pubmed] PHST- 2015/05/20 06:00 [medline] PST - ppublish SO - Zhonghua Xin Xue Guan Bing Za Zhi. 2014 Nov;42(11):927-31.