PMID- 25628847
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150128
LR  - 20221109
IS  - 2008-5230 (Print)
IS  - 2008-5249 (Electronic)
IS  - 2008-5230 (Linking)
VI  - 7
IP  - 1
DP  - 2015 Jan
TI  - Immune-Regulatory Events in the Clearance of HBsAg in Chronic Hepatitis B: 
      Focuses on HLA-DP.
PG  - 5-13
AB  - Successful clearance of hepatitis B virus (HBV) is a promising event in which 
      host's immune system will attempt to get rid of the virus. The immunological 
      events of HBsAg seroclearance have attracted great attention in both natural 
      history investigations and therapeutic trials. Recent genome-wide association 
      studies (GWAS) has confirmed polymorphisms in the human leukocyte antigen 
      (HLA)-DP locus associated with spontaneous HBV clearance. In this review the 
      impact of host immune response in declining HBsAg during the natural history of 
      the infection has been discussed.
FAU - Mohamadkhani, Ashraf
AU  - Mohamadkhani A
AD  - 1. Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases 
      Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
FAU - Katoonizadeh, Aezam
AU  - Katoonizadeh A
AD  - 1. Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases 
      Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
FAU - Poustchi, Hossein
AU  - Poustchi H
AD  - 1. Liver and Pancreatobiliary Diseases Research Center, Digestive Diseases 
      Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - Iran
TA  - Middle East J Dig Dis
JT  - Middle East journal of digestive diseases
JID - 101535395
PMC - PMC4293802
OTO - NOTNLM
OT  - Chronic hepatitis B
OT  - Human leukocyte antigens DP (HLA-DP )
OT  - Immune response
OT  - Polymorphism
EDAT- 2015/01/30 06:00
MHDA- 2015/01/30 06:01
PMCR- 2015/01/01
CRDT- 2015/01/29 06:00
PHST- 2014/10/10 00:00 [received]
PHST- 2014/12/20 00:00 [accepted]
PHST- 2015/01/29 06:00 [entrez]
PHST- 2015/01/30 06:00 [pubmed]
PHST- 2015/01/30 06:01 [medline]
PHST- 2015/01/01 00:00 [pmc-release]
PST - ppublish
SO  - Middle East J Dig Dis. 2015 Jan;7(1):5-13.