PMID- 25629038
OWN - NLM
STAT- MEDLINE
DCOM- 20150928
LR  - 20220330
IS  - 2314-6141 (Electronic)
IS  - 2314-6133 (Print)
VI  - 2015
DP  - 2015
TI  - Gender differences in cerebral regional homogeneity of adult healthy volunteers: 
      a resting-state FMRI study.
PG  - 183074
LID - 10.1155/2015/183074 [doi]
LID - 183074
AB  - OBJECTIVE: We sought to use the regional homogeneity (ReHo) approach as an index 
      in the resting-state functional MRI to investigate the gender differences of 
      spontaneous brain activity within cerebral cortex and resting-state networks 
      (RSNs) in young adult healthy volunteers. METHODS: One hundred and twelve healthy 
      volunteers (56 males, 56 females) participated in the resting-state fMRI scan. 
      The ReHo mappings in the cerebral cortex and twelve RSNs of the male and female 
      groups were compared. RESULTS: We found statistically significant gender 
      differences in the primary visual network (PVN) (P < 0.004, with Bonferroni 
      correction) and left attention network (LAtN), default mode network (DMN), 
      sensorimotor network (SMN), executive network (EN), and dorsal medial prefrontal 
      network (DMPFC) as well (P < 0.05, uncorrected). The male group showed higher 
      ReHo in the left precuneus, while the female group showed higher ReHo in the 
      right middle cingulate gyrus, fusiform gyrus, left inferior parietal lobule, 
      precentral gyrus, supramarginal gyrus, and postcentral gyrus. CONCLUSIONS: Our 
      results suggested that men and women had regional specific differences during the 
      resting-state. The findings may improve our understanding of the gender 
      differences in behavior and cognition from the perspective of resting-state brain 
      function.
FAU - Xu, Chunsheng
AU  - Xu C
AD  - Medical Imaging Center, The First Affiliated Hospital of Anhui University of 
      Chinese Medicine, Anhui 230031, China ; Laboratory of Digital Medical Imaging, 
      The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 
      230031, China ; Institute of Computer Application of Chinese Medicine, Anhui 
      Academy of Chinese Medicine, Anhui 230038, China.
FAU - Li, Chuanfu
AU  - Li C
AD  - Medical Imaging Center, The First Affiliated Hospital of Anhui University of 
      Chinese Medicine, Anhui 230031, China ; Laboratory of Digital Medical Imaging, 
      The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 
      230031, China ; Institute of Computer Application of Chinese Medicine, Anhui 
      Academy of Chinese Medicine, Anhui 230038, China.
FAU - Wu, Hongli
AU  - Wu H
AD  - Laboratory of Digital Medical Imaging, The First Affiliated Hospital of Anhui 
      University of Chinese Medicine, Anhui 230031, China ; Institute of Computer 
      Application of Chinese Medicine, Anhui Academy of Chinese Medicine, Anhui 230038, 
      China.
FAU - Wu, Yuanyuan
AU  - Wu Y
AD  - Graduate School, Anhui University of Chinese Medicine, Anhui 230038, China.
FAU - Hu, Sheng
AU  - Hu S
AD  - Department of Electronic Science and Technology, University of Science & 
      Technology of China, Anhui 230027, China.
FAU - Zhu, Yifang
AU  - Zhu Y
AUID- ORCID: 0000-0002-3484-2631
AD  - Medical Imaging Center, The First Affiliated Hospital of Anhui University of 
      Chinese Medicine, Anhui 230031, China ; Laboratory of Digital Medical Imaging, 
      The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 
      230031, China.
FAU - Zhang, Wei
AU  - Zhang W
AUID- ORCID: 0000-0002-8422-4014
AD  - Medical Imaging Center, The First Affiliated Hospital of Anhui University of 
      Chinese Medicine, Anhui 230031, China.
FAU - Wang, Linying
AU  - Wang L
AUID- ORCID: 0000-0001-8023-0823
AD  - Graduate School, Anhui University of Chinese Medicine, Anhui 230038, China.
FAU - Zhu, Senhua
AU  - Zhu S
AD  - Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
FAU - Liu, Junping
AU  - Liu J
AD  - Medical Imaging Center, The First Affiliated Hospital of Anhui University of 
      Chinese Medicine, Anhui 230031, China ; Laboratory of Digital Medical Imaging, 
      The First Affiliated Hospital of Anhui University of Chinese Medicine, Anhui 
      230031, China.
FAU - Zhang, Qingping
AU  - Zhang Q
AD  - School of Acupuncture & Osteology, Anhui University of Chinese Medicine, Anhui 
      230038, China.
FAU - Yang, Jun
AU  - Yang J
AUID- ORCID: 0000-0002-4849-7402
AD  - Department of Acupuncture and Moxibustion, The First Affiliated Hospital of Anhui 
      University of Chinese Medicine, Anhui 230031, China.
FAU - Zhang, Xiaochu
AU  - Zhang X
AUID- ORCID: 0000-0002-7541-0130
AD  - CAS Key Laboratory of Brain Function & Disease and School of Life Sciences, 
      University of Science & Technology of China, Anhui 230027, China ; Center of 
      Medical Physics and Technology, Hefei Institutes of Physical Science, CAS, Anhui 
      230031, China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150101
PL  - United States
TA  - Biomed Res Int
JT  - BioMed research international
JID - 101600173
SB  - IM
MH  - Adult
MH  - Brain/*anatomy & histology/physiology
MH  - Female
MH  - *Healthy Volunteers
MH  - Humans
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - Monte Carlo Method
MH  - Nerve Net/physiology
MH  - Rest/*physiology
MH  - *Sex Characteristics
MH  - Young Adult
PMC - PMC4299532
EDAT- 2015/01/30 06:00
MHDA- 2015/09/29 06:00
PMCR- 2015/01/01
CRDT- 2015/01/29 06:00
PHST- 2014/05/14 00:00 [received]
PHST- 2014/09/07 00:00 [revised]
PHST- 2014/09/30 00:00 [accepted]
PHST- 2015/01/29 06:00 [entrez]
PHST- 2015/01/30 06:00 [pubmed]
PHST- 2015/09/29 06:00 [medline]
PHST- 2015/01/01 00:00 [pmc-release]
AID - 10.1155/2015/183074 [doi]
PST - ppublish
SO  - Biomed Res Int. 2015;2015:183074. doi: 10.1155/2015/183074. Epub 2015 Jan 1.