PMID- 25629920
OWN - NLM
STAT- MEDLINE
DCOM- 20151007
LR  - 20231110
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 10
IP  - 1
DP  - 2015
TI  - 10-year risk estimation for type 2 diabetes mellitus and coronary heart disease 
      in Kuwait: a cross-sectional population-based study.
PG  - e0116742
LID - 10.1371/journal.pone.0116742 [doi]
LID - e0116742
AB  - BACKGROUND: Type 2 diabetes mellitus (T2DM), coronary heart disease (CHD) and 
      metabolic syndrome (MetS) are major healthcare problems in Kuwait. The present 
      study was designed to determine the prevalence of MetS, and to estimate the 
      10-year risk for developing T2DM and CHD among the general population in Kuwait. 
      METHODS: A descriptive, cross-sectional survey was undertaken in 1800 individuals 
      without diabetes or a history of cardiovascular disease (CVD). They were selected 
      from six governorates using two stage convenience sampling. The questionnaire was 
      developed using the Finnish Diabetes Risk Score (FINDRISK), Framingham Risk Score 
      [FRS] and the 2009 Joint Statement criteria for diagnosis of MetS as a framework. 
      Descriptive and multivariate logistic regression analyses were used. RESULTS: The 
      response rate was 89.4%. More than half (60.8%; 95% CI: 58.4-63.2) of responders 
      were either overweight or obese. One hundred and ninety seven (12.2%) subjects 
      had blood pressure (BP) >/= 140/90 mm Hg. Almost three-in-ten (28.3%: 26.2-30.6) 
      subjects had fasting plasma glucose (FPG) levels >/= 5.6 mmol/l, of whom 86.0% and 
      14.0% had impaired fasting glucose (IFG) and screen detected T2DM, respectively. 
      MetS was present in 512 (31.8%; 29.5-34.2) respondents. Just under one third (n = 
      481; 29.9%; 27.7-32.2) of participants were at moderate, high, or very high risk 
      of developing T2DM, while 283 (17.6%: 15.8-19.6) were at moderate/high 10-year 
      risk of developing CHD. Approximately one-in-ten (8.5%; 7.2-9.9) subjects were at 
      moderate/high/very high 10-year risk of developing both T2DM/CHD. T2DM risk was 
      higher for females compared to males (p < 0.001); however, the pattern was 
      reversed in terms of the risk of developing CHD or T2DM/CHD. The risk of 
      developing T2DM, CHD, or T2DM/CHD was greater among those aged >/= 45 years, and 
      those having MetS (p<0.001). CONCLUSIONS: The current findings highlight the need 
      for multifaceted interventions for prevention.
FAU - Awad, Abdelmoneim Ismail
AU  - Awad AI
AD  - Department of Pharmacy Practice, Faculty of Pharmacy, Kuwait University, Kuwait.
FAU - Alsaleh, Fatemah Mohammad
AU  - Alsaleh FM
AD  - Department of Pharmacy Practice, Faculty of Pharmacy, Kuwait University, Kuwait.
LA  - eng
PT  - Journal Article
DEP - 20150128
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Adult
MH  - Aged
MH  - Aged, 80 and over
MH  - Coronary Disease/diagnosis/*epidemiology
MH  - Cross-Sectional Studies
MH  - Diabetes Mellitus, Type 2/diagnosis/*epidemiology
MH  - Female
MH  - Humans
MH  - Kuwait/epidemiology
MH  - Male
MH  - Middle Aged
MH  - Odds Ratio
MH  - Population Surveillance
MH  - Risk
MH  - Surveys and Questionnaires
MH  - Young Adult
PMC - PMC4309592
COIS- Competing Interests: The authors have declared that no competing interests exist.
EDAT- 2015/01/30 06:00
MHDA- 2015/10/08 06:00
PMCR- 2015/01/28
CRDT- 2015/01/29 06:00
PHST- 2014/03/28 00:00 [received]
PHST- 2014/12/12 00:00 [accepted]
PHST- 2015/01/29 06:00 [entrez]
PHST- 2015/01/30 06:00 [pubmed]
PHST- 2015/10/08 06:00 [medline]
PHST- 2015/01/28 00:00 [pmc-release]
AID - PONE-D-14-13995 [pii]
AID - 10.1371/journal.pone.0116742 [doi]
PST - epublish
SO  - PLoS One. 2015 Jan 28;10(1):e0116742. doi: 10.1371/journal.pone.0116742. 
      eCollection 2015.