PMID- 25630540
OWN - NLM
STAT- MEDLINE
DCOM- 20161213
LR  - 20240324
IS  - 1741-3850 (Electronic)
IS  - 1741-3842 (Print)
IS  - 1741-3842 (Linking)
VI  - 38
IP  - 1
DP  - 2016 Mar
TI  - Crude estimates of cannabis-attributable mortality and morbidity in 
      Canada-implications for public health focused intervention priorities.
PG  - 183-8
LID - 10.1093/pubmed/fdv005 [doi]
AB  - BACKGROUND: Cannabis is the most commonly used drug in Canada; while its use is 
      currently controlled by criminal prohibition, debates about potential control 
      reforms are intensifying. There is substantive evidence about cannabis-related 
      risks to health in various key outcome domains; however, little is known about 
      the actual extent of these harms specifically in Canada. METHODS: Based on 
      epidemiological data (e.g. prevalence of relevant cannabis use rates and relevant 
      risk behaviors; risk ratios; and annual numbers of morbidity/mortality cases in 
      relevant domains), and applying the methodology of comparative risk assessment, 
      we estimated attributable fractions for cannabis-related morbidity and mortality, 
      specifically for: (i) motor-vehicle accidents (MVAs); (ii) use disorders; (iii) 
      mental health (psychosis) and (iv) lung cancer. RESULTS: MVAs and lung cancer are 
      the only domains where cannabis-attributable mortality is estimated to occur. 
      While cannabis use results in morbidity in all domains, MVAs and use disorders by 
      far outweigh the other domains in the number of cases; the popularly debated 
      mental health consequences (e.g., psychosis) translate into relatively small case 
      numbers. CONCLUSIONS: The present crude estimates should guide and help 
      prioritize public health-oriented interventions for the cannabis-related health 
      burden in the population in Canada; formal burden of disease calculations should 
      be conducted.
CI  - (c) The Author 2015. Published by Oxford University Press on behalf of Faculty of 
      Public Health. All rights reserved. For permissions, please e-mail: 
      journals.permissions@oup.com.
FAU - Fischer, Benedikt
AU  - Fischer B
AD  - Social and Epidemiological Research Department, Centre for Addiction and Mental 
      Health, Toronto, Canada M5S 2S1 Centre for Applied Research in Mental Health and 
      Addiction, Faculty of Health Sciences, Simon Fraser University, Vancouver, Canada 
      V6B 5K3 Department of Psychiatry, University of Toronto, Toronto, Canada M5T 1R8.
FAU - Imtiaz, Sameer
AU  - Imtiaz S
AD  - Social and Epidemiological Research Department, Centre for Addiction and Mental 
      Health, Toronto, Canada M5S 2S1 Institute of Medical Science, University of 
      Toronto, Toronto, Canada M5S 1A8.
FAU - Rudzinski, Katherine
AU  - Rudzinski K
AD  - Social and Epidemiological Research Department, Centre for Addiction and Mental 
      Health, Toronto, Canada M5S 2S1 Dalla Lana School of Public Health, University of 
      Toronto, Toronto, Canada M5T 3M7.
FAU - Rehm, Jurgen
AU  - Rehm J
AD  - Social and Epidemiological Research Department, Centre for Addiction and Mental 
      Health, Toronto, Canada M5S 2S1 Department of Psychiatry, University of Toronto, 
      Toronto, Canada M5T 1R8 Institute of Medical Science, University of Toronto, 
      Toronto, Canada M5S 1A8 Dalla Lana School of Public Health, University of 
      Toronto, Toronto, Canada M5T 3M7 WHO/PAHO Collaborating Centre for Mental Health 
      and Addiction, Toronto, Canada M5S 2S1 Klinische Psychologie und Psychotherapie, 
      Technische Universitat Dresden, Dresden 01069, Germany.
LA  - eng
GR  - CPP-85657/Canadian Institutes of Health Research/Canada
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150128
PL  - England
TA  - J Public Health (Oxf)
JT  - Journal of public health (Oxford, England)
JID - 101188638
SB  - IM
MH  - Accidents, Traffic/statistics & numerical data
MH  - Canada/epidemiology
MH  - Female
MH  - Health Priorities
MH  - Humans
MH  - Lung Neoplasms/chemically induced/epidemiology
MH  - Male
MH  - Marijuana Abuse/complications/*epidemiology/mortality/prevention & control
MH  - Mental Disorders/epidemiology
MH  - *Public Health Practice
MH  - Risk Factors
PMC - PMC4750519
OTO - NOTNLM
OT  - Canada
OT  - attributable fractions
OT  - cannabis use
OT  - health risks
OT  - morbidity
OT  - mortality
OT  - public health
EDAT- 2015/01/30 06:00
MHDA- 2016/12/15 06:00
PMCR- 2017/03/01
CRDT- 2015/01/30 06:00
PHST- 2017/03/01 00:00 [pmc-release]
PHST- 2015/01/30 06:00 [entrez]
PHST- 2015/01/30 06:00 [pubmed]
PHST- 2016/12/15 06:00 [medline]
AID - fdv005 [pii]
AID - 10.1093/pubmed/fdv005 [doi]
PST - ppublish
SO  - J Public Health (Oxf). 2016 Mar;38(1):183-8. doi: 10.1093/pubmed/fdv005. Epub 
      2015 Jan 28.