PMID- 25632394 OWN - NLM STAT- MEDLINE DCOM- 20151005 LR - 20181113 IS - 2314-6141 (Electronic) IS - 2314-6133 (Print) VI - 2015 DP - 2015 TI - Quality of life and migraine disability among female migraine patients in a tertiary hospital in Malaysia. PG - 523717 LID - 10.1155/2015/523717 [doi] LID - 523717 AB - BACKGROUND: Disability caused by migraine may be one of the main causes of burden contributing to poor quality of life (QOL) among migraine patients. Thus, this study aimed to measure QOL among migraine sufferers in comparison with healthy controls. METHODS: Female diagnosed migraine patients (n= 100) and healthy controls (n=100) completed the Malay version of the World Health Organization QOL Brief (WHOQOL-BREF) questionnaire. Only migraine patients completed the Malay version of the Migraine Disability Assessment questionnaire. RESULTS: Females with migraines had significantly lower total WHOQOL-BREF scores (84.3) than did healthy controls (91.9, P<0.001). Similarly, physical health (23.4 versus 27.7, P<0.001) and psychological health scores (21.7 versus 23.2, P< 0.001) were significantly lower than those for healthy controls. Seventy-three percent of patients experienced severe disability, with significantly higher number of days with headaches (13.8 days/3 months, P< 0.001) and pain scores (7.4, P< 0.013). Furthermore, migraine patients with lower total QOL scores had 1.2 times higher odds of having disability than patients with higher total QOL scores. CONCLUSIONS: The present study showed that migraine sufferers experienced significantly lower QOL than the control group from a similar population. Disability was severe and frequent and was associated with lower QOL among the migraine patients. FAU - Shaik, Munvar Miya AU - Shaik MM AD - Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia. FAU - Hassan, Norul Badriah AU - Hassan NB AD - Department of Pharmacology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia. FAU - Tan, Huay Lin AU - Tan HL AUID- ORCID: 0000-0002-6670-2668 AD - Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia. FAU - Gan, Siew Hua AU - Gan SH AD - Human Genome Centre, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20150108 PL - United States TA - Biomed Res Int JT - BioMed research international JID - 101600173 SB - IM MH - Adult MH - Demography MH - *Disability Evaluation MH - Female MH - Health Knowledge, Attitudes, Practice MH - Humans MH - Malaysia/epidemiology MH - Middle Aged MH - Migraine Disorders/*epidemiology MH - *Quality of Life MH - Surveys and Questionnaires MH - Tertiary Care Centers/*statistics & numerical data MH - World Health Organization PMC - PMC4302372 EDAT- 2015/01/30 06:00 MHDA- 2015/10/06 06:00 PMCR- 2015/01/08 CRDT- 2015/01/30 06:00 PHST- 2014/09/01 00:00 [received] PHST- 2014/12/18 00:00 [accepted] PHST- 2015/01/30 06:00 [entrez] PHST- 2015/01/30 06:00 [pubmed] PHST- 2015/10/06 06:00 [medline] PHST- 2015/01/08 00:00 [pmc-release] AID - 10.1155/2015/523717 [doi] PST - ppublish SO - Biomed Res Int. 2015;2015:523717. doi: 10.1155/2015/523717. Epub 2015 Jan 8.