PMID- 25635985 OWN - NLM STAT- MEDLINE DCOM- 20150604 LR - 20220408 IS - 2284-0729 (Electronic) IS - 1128-3602 (Linking) VI - 19 IP - 1 DP - 2015 Jan TI - Effect of environmental air pollution on type 2 diabetes mellitus. PG - 123-8 LID - 8346 [pii] AB - OBJECTIVE: Air pollution is a novel risk factor for insulin resistance and occurrence of type 2 diabetes mellitus (T2DM), but the evidence is limited and diverse. Therefore, the aim of this study was to assess the effect of environmental air pollution on incidence of type 2 diabetes mellitus. METHODS: In this study, we identified 102 published studies through a systematic data base search including ISI-Web of Science, EMBASE and PubMed. We searched the related literature by using the key terms including diabetes mellitus, air pollution, occupational and environmental pollution, gaseous, NO2, particulate matter pollutants PM2.5, and PM10. Studies in which diabetes mellitus, insulin resistance, air pollution, occupational and environmental pollution was discussed were included in the study. No confines on publication status, study design or language of publication were considered. Descriptive and quantitative information were extracted from the selected literature. Finally we included 21 publications and remaining studies were excluded. RESULTS: Air pollution is a leading cause of insulin resistance and incidence of type 2 diabetes mellitus. The association between air pollution and diabetes is stronger for traffic associated pollutants, gaseous, nitrogen dioxide, tobacco smoke and particulate matter. CONCLUSIONS: Exposure to air pollutants is significantly associated with increased risk of type 2 diabetes mellitus. It is suggested that, environmental protection officials must take high priority steps to minimize the air pollution, hence to decrease the incidence of type 2 diabetes mellitus. FAU - Meo, S A AU - Meo SA AD - Department of Physiology, Pharmacology, University Diabetes Centre; College of Medicine, King Saud University, Riyadh, Saudi Arabia. sultanmeo@hotmail.com. FAU - Memon, A N AU - Memon AN FAU - Sheikh, S A AU - Sheikh SA FAU - Rouq, F A AU - Rouq FA FAU - Usmani, A Mahmood AU - Usmani AM FAU - Hassan, A AU - Hassan A FAU - Arian, S A AU - Arian SA LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Italy TA - Eur Rev Med Pharmacol Sci JT - European review for medical and pharmacological sciences JID - 9717360 RN - 0 (Air Pollutants) RN - 0 (Particulate Matter) RN - S7G510RUBH (Nitrogen Dioxide) SB - IM MH - Air Pollutants/*analysis MH - Air Pollution/*statistics & numerical data MH - Diabetes Mellitus, Type 2/*epidemiology/etiology MH - Humans MH - Incidence MH - Nitrogen Dioxide/analysis MH - Particulate Matter/analysis MH - Risk Factors EDAT- 2015/01/31 06:00 MHDA- 2015/06/05 06:00 CRDT- 2015/01/31 06:00 PHST- 2015/01/31 06:00 [entrez] PHST- 2015/01/31 06:00 [pubmed] PHST- 2015/06/05 06:00 [medline] AID - 8346 [pii] PST - ppublish SO - Eur Rev Med Pharmacol Sci. 2015 Jan;19(1):123-8.