PMID- 25636572
OWN - NLM
STAT- MEDLINE
DCOM- 20160114
LR  - 20150330
IS  - 1879-1166 (Electronic)
IS  - 0198-8859 (Linking)
VI  - 76
IP  - 4
DP  - 2015 Apr
TI  - HLA-DQA1, DQB1 and DRB1 alleles associated with Takayasu arteritis in the Chinese 
      Han population.
PG  - 241-4
LID - S0198-8859(15)00009-9 [pii]
LID - 10.1016/j.humimm.2015.01.008 [doi]
AB  - Takayasu arteritis (TA) is a chronic large-vessel vasculitis of unknown etiology. 
      Human leukocyte antigen (HLA) alleles play an important role in the development 
      of TA. Sequence specific primer-polymerase chain reaction was used to detect 10 
      alleles of the HLA-DQA1 gene and 13 alleles of the HLA-DQB1, -DRB1 gene. A 
      significant increase in the frequencies of DRB1( *)07 (Pc<0.01, OR=3.44, CI: 
      2.15-5.52) was observed among TA patients compared with the control group. The 
      significantly increased frequencies of the haplotype 
      DQA1( *)03:01-DQB1( *)03:01-DRB1( *)07 (Corrected P-values<0.01) were observed in TA 
      patients. But in the analysis of clinical manifestations, there are no 
      significant associations with the HLA-DRB1( *)07 allele.
CI  - Copyright (c) 2015 American Society for Histocompatibility and Immunogenetics. 
      Published by Elsevier Inc. All rights reserved.
FAU - Lv, Naqiang
AU  - Lv N
AD  - State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai 
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical 
      Sciences and Peking Union Medical College, Beijing 100037, People's Republic of 
      China.
FAU - Wang, Zhiguang
AU  - Wang Z
AD  - State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai 
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical 
      Sciences and Peking Union Medical College, Beijing 100037, People's Republic of 
      China.
FAU - Dang, Aimin
AU  - Dang A
AD  - State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai 
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical 
      Sciences and Peking Union Medical College, Beijing 100037, People's Republic of 
      China.
FAU - Zhu, Xilin
AU  - Zhu X
AD  - National Laboratory of Medical Molecular Biology and Institute of Basic Medical 
      Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking 
      Union Medical College, Beijing 100730, People's Republic of China.
FAU - Liu, Ying
AU  - Liu Y
AD  - National Laboratory of Medical Molecular Biology and Institute of Basic Medical 
      Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking 
      Union Medical College, Beijing 100730, People's Republic of China.
FAU - Zheng, Deyu
AU  - Zheng D
AD  - State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai 
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical 
      Sciences and Peking Union Medical College, Beijing 100037, People's Republic of 
      China.
FAU - Liu, Guozhang
AU  - Liu G
AD  - State Key Laboratory of Cardiovascular Disease, Department of Cardiology, Fuwai 
      Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical 
      Sciences and Peking Union Medical College, Beijing 100037, People's Republic of 
      China.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150127
PL  - United States
TA  - Hum Immunol
JT  - Human immunology
JID - 8010936
RN  - 0 (HLA-DQ alpha-Chains)
RN  - 0 (HLA-DQ beta-Chains)
RN  - 0 (HLA-DQA1 antigen)
RN  - 0 (HLA-DQB1 antigen)
RN  - 0 (HLA-DRB1 Chains)
SB  - IM
MH  - Adult
MH  - Alleles
MH  - China
MH  - DNA Mutational Analysis
MH  - Female
MH  - Gene Frequency
MH  - Genetic Association Studies
MH  - Genetic Predisposition to Disease
MH  - Genotype
MH  - HLA-DQ alpha-Chains/*genetics
MH  - HLA-DQ beta-Chains/*genetics
MH  - HLA-DRB1 Chains/*genetics
MH  - Humans
MH  - Male
MH  - Middle Aged
MH  - Polymorphism, Genetic
MH  - Takayasu Arteritis/*genetics
MH  - Young Adult
OTO - NOTNLM
OT  - Chinese Han population
OT  - DQA1
OT  - DQB1
OT  - DRB1
OT  - Takayasu arteritis
EDAT- 2015/02/01 06:00
MHDA- 2016/01/15 06:00
CRDT- 2015/02/01 06:00
PHST- 2014/04/04 00:00 [received]
PHST- 2014/12/31 00:00 [revised]
PHST- 2015/01/14 00:00 [accepted]
PHST- 2015/02/01 06:00 [entrez]
PHST- 2015/02/01 06:00 [pubmed]
PHST- 2016/01/15 06:00 [medline]
AID - S0198-8859(15)00009-9 [pii]
AID - 10.1016/j.humimm.2015.01.008 [doi]
PST - ppublish
SO  - Hum Immunol. 2015 Apr;76(4):241-4. doi: 10.1016/j.humimm.2015.01.008. Epub 2015 
      Jan 27.