PMID- 25652419 OWN - NLM STAT- MEDLINE DCOM- 20160127 LR - 20181113 IS - 1573-0832 (Electronic) IS - 0301-486X (Linking) VI - 179 IP - 5-6 DP - 2015 Jun TI - Synchronous oral paracoccidioidomycosis and pulmonary tuberculosis in an immunocompetent patient. PG - 459-64 LID - 10.1007/s11046-015-9868-3 [doi] AB - Paracoccidioidomycosis (PCM) and tuberculosis (TB) are chronic granulomatous infectious diseases, in which the main form of contraction is through inhalation of the microorganism-Paracoccidioides brasiliensis and Mycobacterium tuberculosis. Oral involvement of PCM is observed in up to 70 % of the cases and usually presents clinically as ulcerations with granular surface showing tiny hemorrhagic areas. Oral presentation of TB is rare with prevalence smaller than 0.5 % of all cases. Clinical presentation of oral TB mainly consists of single ulcers with irregular limits and necrotic base. A 70-year-old immunocompetent man presented simultaneously oral PCM and pulmonary TB. Medical history revealed a previous diagnosis of pulmonary TB; however, even under treatment for TB, the patient remained with oral lesions and intense pulmonary fibrosis. The physician requested P. brasiliensis serological analysis, which resulted positive. Although the combination of PCM and TB has been reported in the literature, it is still considered an uncommon condition and their diagnosis may represent a challenge to healthcare professionals because of the similarity between their clinical and radiological presentations. FAU - Amorim Pellicioli, Ana Carolina AU - Amorim Pellicioli AC AD - Piracicaba Dental School, State University of Campinas - UNICAMP, Piracicaba, Brazil. FAU - Neves-Silva, Rodrigo AU - Neves-Silva R FAU - Santos-Silva, Alan Roger AU - Santos-Silva AR FAU - Vargas, Pablo Agustin AU - Vargas PA FAU - Lopes, Marcio Ajudarte AU - Lopes MA LA - eng PT - Case Reports PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20150205 PL - Netherlands TA - Mycopathologia JT - Mycopathologia JID - 7505689 SB - IM MH - Aged MH - Histocytochemistry MH - Humans MH - Lung/pathology MH - Male MH - Microscopy MH - Mouth Diseases/complications/diagnosis/pathology MH - Mycobacterium tuberculosis/*isolation & purification MH - Paracoccidioides/*isolation & purification MH - Paracoccidioidomycosis/*complications/*diagnosis/pathology MH - Radiography, Thoracic MH - Tuberculosis, Pulmonary/*complications/*diagnosis/pathology EDAT- 2015/02/06 06:00 MHDA- 2016/01/28 06:00 CRDT- 2015/02/06 06:00 PHST- 2014/07/29 00:00 [received] PHST- 2015/01/27 00:00 [accepted] PHST- 2015/02/06 06:00 [entrez] PHST- 2015/02/06 06:00 [pubmed] PHST- 2016/01/28 06:00 [medline] AID - 10.1007/s11046-015-9868-3 [doi] PST - ppublish SO - Mycopathologia. 2015 Jun;179(5-6):459-64. doi: 10.1007/s11046-015-9868-3. Epub 2015 Feb 5.