PMID- 2565877
OWN - NLM
STAT- MEDLINE
DCOM- 19890612
LR  - 20190903
IS  - 0888-7543 (Print)
IS  - 0888-7543 (Linking)
VI  - 4
IP  - 3
DP  - 1989 Apr
TI  - Linkage analysis of multiple endocrine neoplasia type 1 with INT2 and other 
      markers on chromosome 11.
PG  - 320-2
AB  - We evaluated linkage between the locus for multiple endocrine neoplasia type 1 
      (MEN1) and several polymorphic DNA markers on chromosome 11 in a single large 
      pedigree. On the basis of the finding of a basic fibroblast growth factor 
      (bFGF)-like substance circulating in plasma of MEN1 patients, we chose a 
      bFGF-related gene known to be localized to 11q13 as one of the markers. This gene 
      locus, INT2, was found to be closely linked to the MEN1 gene. Pairwise and 
      multipoint analyses with INT2 confirm the recent finding by C. Larsson et al. 
      (1988, Nature (London) 332: 85-87) of MEN1 linkage to another marker, skeletal 
      muscle glycogen phosphorylase, at 11q13.
FAU - Bale, S J
AU  - Bale SJ
AD  - Family Studies Section, National Cancer Institute, Bethesda, Maryland 20892.
FAU - Bale, A E
AU  - Bale AE
FAU - Stewart, K
AU  - Stewart K
FAU - Dachowski, L
AU  - Dachowski L
FAU - McBride, O W
AU  - McBride OW
FAU - Glaser, T
AU  - Glaser T
FAU - Green, J E 3rd
AU  - Green JE 3rd
FAU - Mulvihill, J J
AU  - Mulvihill JJ
FAU - Brandi, M L
AU  - Brandi ML
FAU - Sakaguchi, K
AU  - Sakaguchi K
AU  - et al.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Genomics
JT  - Genomics
JID - 8800135
RN  - 0 (Genetic Markers)
RN  - EC 2.4.1.- (Phosphorylases)
SB  - IM
EIN - Genomics 1989 Jul;5(1):166
MH  - *Chromosomes, Human, Pair 11
MH  - Female
MH  - Genetic Markers
MH  - Humans
MH  - Lod Score
MH  - Male
MH  - Multiple Endocrine Neoplasia/*genetics
MH  - Pedigree
MH  - Phosphorylases/genetics
MH  - Polymorphism, Restriction Fragment Length
EDAT- 1989/04/01 00:00
MHDA- 1989/04/01 00:01
CRDT- 1989/04/01 00:00
PHST- 1989/04/01 00:00 [pubmed]
PHST- 1989/04/01 00:01 [medline]
PHST- 1989/04/01 00:00 [entrez]
AID - 10.1016/0888-7543(89)90336-4 [doi]
PST - ppublish
SO  - Genomics. 1989 Apr;4(3):320-2. doi: 10.1016/0888-7543(89)90336-4.