PMID- 25660823
OWN - NLM
STAT- MEDLINE
DCOM- 20151120
LR  - 20150209
IS  - 1423-0275 (Electronic)
IS  - 0301-1569 (Linking)
VI  - 77
IP  - 1
DP  - 2015
TI  - Allergogenic profile in patients with different subtypes of chronic 
      rhinosinusitis with nasal polyps.
PG  - 10-6
LID - 10.1159/000370121 [doi]
AB  - AIMS: The aim of this study was to analyze the relationship between allergy and 
      different subtypes of chronic rhinosinusitis with nasal polyps (CRSwNP). METHODS: 
      A total of 83 patients with CRSwNP and 20 patients with nasal septum deviation 
      (NSD) as controls were enrolled in our study. Nasal tissue was obtained from all 
      subjects during surgery. Hematoxylin and eosin staining was performed and the 
      CRSwNP cases were classified into eosinophilic nasal polyps (ENP) and 
      noneosinophilic nasal polyps (nENP) cases according to the percent of 
      eosinophils. The Allergy Screen test was used to detect total and specific 
      immunoglobulin E (IgE) against 5 kinds of common inhalant allergens. RESULTS: 
      There were 28 (33.73%) patients with ENP and 55 with nENP. Total IgE levels were 
      significantly increased in ENP compared with nENP patients. The IgE level was 
      significantly correlated with the eosinophil count. According to the 5 kinds of 
      common inhalant allergens, only ENP patients exhibited higher sensitivity to dust 
      mites. CONCLUSION: Patients with ENP showed significantly higher IgE levels when 
      compared with patients with nENP based on allergy.
CI  - (c) 2015 S. Karger AG, Basel.
FAU - Xu, Ming
AU  - Xu M
AD  - Department of Otorhinolaryngology, the Affiliated Hospital of the Medical School 
      of Ningbo University, Ningbo, China.
FAU - Ye, Xiaolei
AU  - Ye X
FAU - Zhao, Feng
AU  - Zhao F
FAU - He, Yong
AU  - He Y
FAU - Chen, Lei
AU  - Chen L
LA  - eng
PT  - Journal Article
DEP - 20150130
PL  - Switzerland
TA  - ORL J Otorhinolaryngol Relat Spec
JT  - ORL; journal for oto-rhino-laryngology and its related specialties
JID - 0334721
RN  - 0 (Allergens)
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - Aged
MH  - Allergens/*immunology
MH  - Case-Control Studies
MH  - Chronic Disease
MH  - Eosinophilia/blood/complications/*immunology
MH  - Female
MH  - Humans
MH  - Hypersensitivity/blood/diagnosis/*etiology
MH  - Immunoglobulin E/blood
MH  - Leukocyte Count
MH  - Male
MH  - Middle Aged
MH  - Nasal Polyps/blood/complications/*immunology
MH  - Rhinitis/blood/complications/*immunology
MH  - Sinusitis/blood/complications/*immunology
MH  - Young Adult
EDAT- 2015/02/11 06:00
MHDA- 2015/12/15 06:00
CRDT- 2015/02/10 06:00
PHST- 2014/05/09 00:00 [received]
PHST- 2014/11/24 00:00 [accepted]
PHST- 2015/02/10 06:00 [entrez]
PHST- 2015/02/11 06:00 [pubmed]
PHST- 2015/12/15 06:00 [medline]
AID - 000370121 [pii]
AID - 10.1159/000370121 [doi]
PST - ppublish
SO  - ORL J Otorhinolaryngol Relat Spec. 2015;77(1):10-6. doi: 10.1159/000370121. Epub 
      2015 Jan 30.