PMID- 25661801
OWN - NLM
STAT- MEDLINE
DCOM- 20151001
LR  - 20191210
IS  - 1873-6254 (Electronic)
IS  - 0001-706X (Print)
IS  - 0001-706X (Linking)
VI  - 145
DP  - 2015 May
TI  - Independent evaluation of a canine Echinococcosis Control Programme in Hobukesar 
      County, Xinjiang, China.
PG  - 1-7
LID - S0001-706X(15)00010-8 [pii]
LID - 10.1016/j.actatropica.2015.01.009 [doi]
AB  - The Xinjiang Uyghur Autonomous Region in northwest China is one of the world's 
      most important foci for cystic echinococcosis. Domestic dogs are the main source 
      for human infection, and previous studies in Xinjiang have found a canine 
      Echinococcus spp. coproELISA prevalence of between 36% and 41%. In 2010 the 
      Chinese National Echinococcosis Control Programme was implemented in Xinjiang, 
      and includes regular dosing of domestic dogs with praziquantel. Six communities 
      in Hobukesar County, northwest Xinjiang were assessed in relation to the impact 
      of this control programme through dog necropsies, dog Echinococcus spp. 
      coproantigen surveys based on Lot Quality Assurance Sampling (LQAS) and dog owner 
      questionnaires. We found that 42.1% of necropsied dogs were infected with 
      Echinococcus granulosus, and coproELISA prevalences were between 15% and 70% in 
      the communities. Although approximately half of all dog owners reported dosing 
      their dogs within the 12 months prior to sampling, coproELISA prevalence remained 
      high. Regular praziquantel dosing of owned dogs in remote and semi-nomadic 
      communities such as those in Hobukesar County is logistically very difficult and 
      additional measures should be considered to reduce canine echinococcosis.
CI  - Copyright (c) 2015 The Authors. Published by Elsevier B.V. All rights reserved.
FAU - van Kesteren, Freya
AU  - van Kesteren F
AD  - Cestode Zoonoses Research Group, School of Environment and Life Sciences, 
      University of Salford, M5 4WT Salford, UK. Electronic address: 
      Freyavankesteren@gmail.com.
FAU - Qi, Xinwei
AU  - Qi X
AD  - State Key Lab Incubation Base for Xinjiang Major Diseases Research and Xinjiang 
      Key Laboratory of Echinococcosis, the First Affiliated Hospital of Xinjiang 
      Medical University, Urumqi, Xinjiang, China.
FAU - Tao, Jiang
AU  - Tao J
AD  - State Key Lab Incubation Base for Xinjiang Major Diseases Research and Xinjiang 
      Key Laboratory of Echinococcosis, the First Affiliated Hospital of Xinjiang 
      Medical University, Urumqi, Xinjiang, China.
FAU - Feng, Xiaohui
AU  - Feng X
AD  - State Key Lab Incubation Base for Xinjiang Major Diseases Research and Xinjiang 
      Key Laboratory of Echinococcosis, the First Affiliated Hospital of Xinjiang 
      Medical University, Urumqi, Xinjiang, China.
FAU - Mastin, Alexander
AU  - Mastin A
AD  - Cestode Zoonoses Research Group, School of Environment and Life Sciences, 
      University of Salford, M5 4WT Salford, UK.
FAU - Craig, Philip S
AU  - Craig PS
AD  - Cestode Zoonoses Research Group, School of Environment and Life Sciences, 
      University of Salford, M5 4WT Salford, UK.
FAU - Vuitton, Dominique A
AU  - Vuitton DA
AD  - WHO-Collaborating Centre for Prevention and Treatment of Human Echinococcosis, 
      France.
FAU - Duan, Xinyu
AU  - Duan X
AD  - State Key Lab Incubation Base for Xinjiang Major Diseases Research and Xinjiang 
      Key Laboratory of Echinococcosis, the First Affiliated Hospital of Xinjiang 
      Medical University, Urumqi, Xinjiang, China.
FAU - Chu, Xiangdong
AU  - Chu X
AD  - People's Hospital of Hobukesar County, Hobukesar, Xinjiang, China.
FAU - Zhu, Jinlong
AU  - Zhu J
AD  - People's Hospital of Hobukesar County, Hobukesar, Xinjiang, China.
FAU - Wen, Hao
AU  - Wen H
AD  - State Key Lab Incubation Base for Xinjiang Major Diseases Research and Xinjiang 
      Key Laboratory of Echinococcosis, the First Affiliated Hospital of Xinjiang 
      Medical University, Urumqi, Xinjiang, China. Electronic address: 
      dr.wenhao@163.com.
LA  - eng
GR  - 094325/Z/10/Z/Wellcome Trust/United Kingdom
PT  - Evaluation Study
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20150207
PL  - Netherlands
TA  - Acta Trop
JT  - Acta tropica
JID - 0370374
RN  - 6490C9U457 (Praziquantel)
SB  - IM
MH  - Animals
MH  - China/epidemiology
MH  - Dog Diseases/*drug therapy/*epidemiology
MH  - Dogs
MH  - Echinococcosis/drug therapy/*epidemiology/*veterinary
MH  - Echinococcus granulosus/*drug effects
MH  - Humans
MH  - Lot Quality Assurance Sampling
MH  - Praziquantel/*therapeutic use
MH  - Prevalence
MH  - Surveys and Questionnaires
MH  - Zoonoses/*prevention & control
PMC - PMC4380135
OTO - NOTNLM
OT  - Control programme
OT  - Domestic dogs
OT  - Echinococcus granulosus
OT  - Lot Quality Assurance Sampling
OT  - Xinjiang
EDAT- 2015/02/11 06:00
MHDA- 2015/10/02 06:00
PMCR- 2015/05/01
CRDT- 2015/02/10 06:00
PHST- 2014/07/22 00:00 [received]
PHST- 2014/12/17 00:00 [revised]
PHST- 2015/01/24 00:00 [accepted]
PHST- 2015/02/10 06:00 [entrez]
PHST- 2015/02/11 06:00 [pubmed]
PHST- 2015/10/02 06:00 [medline]
PHST- 2015/05/01 00:00 [pmc-release]
AID - S0001-706X(15)00010-8 [pii]
AID - 10.1016/j.actatropica.2015.01.009 [doi]
PST - ppublish
SO  - Acta Trop. 2015 May;145:1-7. doi: 10.1016/j.actatropica.2015.01.009. Epub 2015 
      Feb 7.