PMID- 25664459 OWN - NLM STAT- MEDLINE DCOM- 20160217 LR - 20181113 IS - 1916-7245 (Electronic) IS - 1198-2241 (Print) IS - 1198-2241 (Linking) VI - 22 IP - 1 DP - 2015 Jan-Feb TI - Primary pulmonary synovial sarcoma: a case report with unique and impressive computed tomography findings. PG - e1-3 AB - Primary pulmonary synovial sarcoma (PPSS) is a rare malignancy. Its etiology, imaging features and optimal treatment are not well understood. Pulmonary pseudoaneurysms and lymphadenopathy are rare complications of synovial sarcomas. A 40-year-old woman with mild hemoptysis and thoracic back pain underwent a computed tomography scan that revealed multiple pulmonary lesions, paraesophageal lymphadenopathy and incidental bilateral pulmonary emboli. A diagnosis of PPSS was made through the identification of an SS18 translocation by fluorescence in situ hybridization. She was started on adriamycin, ifosfamide and mesna chemotherapy. Over the subsequent two months, she developed three pulmonary artery pseudoaneurysms, ultimately requiring endovascular coiling. Seven months after starting treatment, the patient was asymptomatic. The lesions and lymphadenopathy decreased in size. The present case highlights complications of a rare malignancy and demonstrates positive response to ifosfamide-based chemotherapy in the setting of PPSS. FAU - Kambo, Jaspreet S AU - Kambo JS FAU - Richardson, Bonnie AU - Richardson B FAU - Ionescu, Diana N AU - Ionescu DN FAU - Tucker, Tracy AU - Tucker T FAU - Kraushaar, Greg AU - Kraushaar G LA - eng PT - Case Reports PT - Journal Article PL - Egypt TA - Can Respir J JT - Canadian respiratory journal JID - 9433332 RN - 0 (Antineoplastic Agents) SB - IM MH - Adult MH - Aneurysm, False/etiology/therapy MH - Antineoplastic Agents/therapeutic use MH - Endovascular Procedures MH - Female MH - Humans MH - Lung Neoplasms/complications/*diagnostic imaging/drug therapy MH - Pulmonary Artery MH - Radiography MH - Sarcoma, Synovial/complications/*diagnostic imaging/drug therapy PMC - PMC4324527 EDAT- 2015/02/11 06:00 MHDA- 2016/02/18 06:00 PMCR- 2015/07/01 CRDT- 2015/02/10 06:00 PHST- 2015/02/10 06:00 [entrez] PHST- 2015/02/11 06:00 [pubmed] PHST- 2016/02/18 06:00 [medline] PHST- 2015/07/01 00:00 [pmc-release] AID - crj-22-e1 [pii] AID - 10.1155/2015/231043 [doi] PST - ppublish SO - Can Respir J. 2015 Jan-Feb;22(1):e1-3. doi: 10.1155/2015/231043.