PMID- 25664999 OWN - NLM STAT- MEDLINE DCOM- 20160119 LR - 20150501 IS - 1439-3964 (Electronic) IS - 0172-4622 (Linking) VI - 36 IP - 5 DP - 2015 May TI - The Effect of Fish Oil, Vitamin D and Protein on URTI Incidence in Young Active People. PG - 426-30 LID - 10.1055/s-0034-1394464 [doi] AB - Upper respiratory tract infections (URTI) are a frequent illness among athletes. We investigated the effect of a multi-nutrient supplement (vitamin D, fish oil and protein) on the occurrence of URTI in young active people. 42 young recreational athletes were randomly assigned to receive either supplementation (550 mg DHA, 550 mg EPA, 10 microg vitamin D3 and 8 g whey protein) or placebo for 16 weeks. Unstimulated saliva samples were collected by passive drool. Samples were analysed for IgA (sIgA) concentration and the secretion rate extrapolated by multiplying concentration by saliva flow rate. Physical activity levels and URTI incidence were monitored by questionnaire. Training status was not different between the 2 groups. There were no differences in the incidence, severity and duration of URTI. However the number of symptom days was lower in the supplemented compared to the control group (1.72+/-1.67 vs. 2.79+/-1.76; P<0.05). sIgA concentration and secretion rate did not differ between groups. This study demonstrates that 16 weeks of supplementation with fish oil, vitamin D and protein did not modify the incidence, severity and duration of URTI, although the total number of symptom days was reduced, in a healthy active population. CI - (c) Georg Thieme Verlag KG Stuttgart . New York. FAU - Da Boit, M AU - Da Boit M AD - Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom. FAU - Gabriel, B M AU - Gabriel BM AD - Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom. FAU - Gray, P AU - Gray P AD - Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom. FAU - Gray, S R AU - Gray SR AD - Institute of Medical Sciences, University of Aberdeen, Aberdeen, United Kingdom. LA - eng PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, Non-U.S. Gov't DEP - 20150209 PL - Germany TA - Int J Sports Med JT - International journal of sports medicine JID - 8008349 RN - 0 (Fish Oils) RN - 0 (Immunoglobulin A, Secretory) RN - 0 (Whey Proteins) RN - 1406-16-2 (Vitamin D) SB - IM MH - Adult MH - Age Factors MH - Body Mass Index MH - *Dietary Supplements MH - Female MH - Fish Oils/*administration & dosage MH - Humans MH - Immunoglobulin A, Secretory/analysis MH - Incidence MH - Male MH - Motor Activity/*physiology MH - Respiratory Tract Infections/*epidemiology MH - Saliva/immunology MH - Time Factors MH - Vitamin D/*administration & dosage MH - Whey Proteins/*administration & dosage MH - Young Adult EDAT- 2015/02/11 06:00 MHDA- 2016/01/20 06:00 CRDT- 2015/02/10 06:00 PHST- 2015/02/10 06:00 [entrez] PHST- 2015/02/11 06:00 [pubmed] PHST- 2016/01/20 06:00 [medline] AID - 10.1055/s-0034-1394464 [doi] PST - ppublish SO - Int J Sports Med. 2015 May;36(5):426-30. doi: 10.1055/s-0034-1394464. Epub 2015 Feb 9.