PMID- 25670912
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20150211
LR  - 20200930
IS  - 1178-7074 (Print)
IS  - 1178-7074 (Electronic)
IS  - 1178-7074 (Linking)
VI  - 8
DP  - 2015
TI  - Association between the ankle-brachial index, intermittent claudication, and 
      physical activity level: what is the influence on the functional capacity of 
      patients with or at high risk of cardiovascular disease?
PG  - 55-62
LID - 10.2147/IJGM.S76446 [doi]
AB  - BACKGROUND: Patients with or at high risk of cardiovascular disease have a poor 
      functional capacity; however, the influence of association among intermittent 
      claudication (IC), abnormal ankle-brachial index (ABI), and physical activity 
      level on functional capacity of these patients has not been fully studied. 
      OBJECTIVE: The primary objective of this study was to investigate the association 
      between the ABI, IC, and physical activity level, and the influence of these 
      variables on the functional capacity of patients with or at high risk of 
      cardiovascular disease seen in a reference cardiology outpatient clinic in 
      Southern Brazil. The secondary objective was to assess the prevalence of 
      peripheral arterial disease (PAD) in this sample of patients. PATIENTS AND 
      METHODS: This was a prospective cross-sectional study in which 162 consecutive 
      patients were evaluated and classified into three groups according to their ABI: 
      normal ABI (n=104, values between 1.00 and 1.40); borderline PAD (n=23, values 
      between 0.91 and 1.00); and patients with PAD (n=35, </=0.90). The presence of IC 
      was assessed using the Edinburgh Claudication Questionnaire. The level of 
      physical activity was assessed by the short version of the International Physical 
      Activity Questionnaire (IPAQ) and functional capacity was assessed by the 
      6-minute walk distance (6MWD). RESULTS: The prevalence of PAD was 21.6% in the 
      total sample. The 6MWD showed strong correlation with the absence of IC (r=0.785; 
      P<0.001), moderate correlation with age (r=-0.347; P<0.001), and weak 
      correlations with IPAQ scores (r=0.164; P=0.038) and ABI (r=0.216; P=0.006). Age, 
      ABI, and absence of IC were independently associated with the outcome (P=0.001, 
      P=0.001, and P=0.028, respectively). CONCLUSION: The current study demonstrates 
      that 6MWD is associated with IPAQ scores, ABI, and absence of IC. Age, ABI and 
      absence of IC were independently associated with functional capacity in patients 
      with or at high risk of cardiovascular disease.
FAU - Nardi Gomes, Tiago Jose
AU  - Nardi Gomes TJ
AD  - Department of Physiotherapy, UNIFRA, Centro Universitario Franciscano, Santa 
      Maria, RS, Brazil.
FAU - Martins de Albuquerque, Isabella
AU  - Martins de Albuquerque I
AD  - Department of Physiotherapy and Rehabilitation, Universidade Federal de Santa 
      Maria, Santa Maria, RS, Brazil.
FAU - de Moraes Costa, Patricia
AU  - de Moraes Costa P
AD  - Department of Clinical Medicine, Universidade Federal de Santa Maria, Santa 
      Maria, RS, Brazil.
FAU - Cardoso, Dannuey Machado
AU  - Cardoso DM
AD  - Department of Physiotherapy, Universidade de Santa Cruz do Sul, Santa Cruz do 
      Sul, RS, Brazil.
FAU - de Moraes Costa, Gabriela
AU  - de Moraes Costa G
AD  - Department of Neuropsychiatry, Universidade Federal de Santa Maria, Santa Maria, 
      RS, Brazil.
FAU - da Costa Vieira, Jose Luiz
AU  - da Costa Vieira JL
AD  - Fundacao Universitaria de Cardiologia, Instituto de Cardiologia, Porto Alegre, 
      RS, Brazil.
LA  - eng
PT  - Journal Article
DEP - 20150123
PL  - New Zealand
TA  - Int J Gen Med
JT  - International journal of general medicine
JID - 101515487
PMC - PMC4315558
OTO - NOTNLM
OT  - 6-minute walk test
OT  - IPAQ
OT  - cardiology outpatient clinic
OT  - peripheral arterial disease
EDAT- 2015/02/12 06:00
MHDA- 2015/02/12 06:01
PMCR- 2015/01/23
CRDT- 2015/02/12 06:00
PHST- 2015/02/12 06:00 [entrez]
PHST- 2015/02/12 06:00 [pubmed]
PHST- 2015/02/12 06:01 [medline]
PHST- 2015/01/23 00:00 [pmc-release]
AID - ijgm-8-055 [pii]
AID - 10.2147/IJGM.S76446 [doi]
PST - epublish
SO  - Int J Gen Med. 2015 Jan 23;8:55-62. doi: 10.2147/IJGM.S76446. eCollection 2015.