PMID- 25672373
OWN - NLM
STAT- MEDLINE
DCOM- 20160325
LR  - 20161125
IS  - 1477-0962 (Electronic)
IS  - 0961-2033 (Linking)
VI  - 24
IP  - 8
DP  - 2015 Jul
TI  - Spontaneous coronary artery thrombosis in the setting of active lupus mesenteric 
      vasculitis.
PG  - 885-8
LID - 10.1177/0961203315570167 [doi]
AB  - A 33-year-old male with systemic lupus erythematosus (SLE) presented with acute 
      abdominal pain and was found to have lupus mesenteric vasculitis on imaging and 
      during exploratory laparotomy. Post laparotomy he continued to have persistent 
      nausea and dyspepsia and an electrocardiogram showed evidence of an inferior ST 
      elevation myocardial infarction (STEMI). Emergency cardiac catheterization showed 
      evidence of thrombotic right coronary artery occlusion. His coronaries were 
      otherwise normal with no evidence of underlying coronary artery disease. 
      Extensive workup with trans-esophageal echo, serologies for antiphospholipid 
      antibody syndrome (APS) and bubble study was negative. This effectively ruled out 
      Libman-Sacks endocarditis, APS-induced arterial thrombus and paradoxical emboli 
      as potential causes of his STEMI. By exclusion of other causes, the etiology of 
      his STEMI was felt to be secondary to in-situ coronary artery thrombosis in the 
      setting of active SLE. To the best of our knowledge, this is the first report of 
      a patient with SLE presenting with both lupus mesenteric vasculitis and in-situ 
      coronary arterial thrombosis in the absence of APS.
CI  - (c) The Author(s) 2015.
FAU - Reddy, Yogesh N V
AU  - Reddy YN
AD  - Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, USA 
      Reddy.yogesh@mayo.edu.
FAU - Sundaram, V
AU  - Sundaram V
AD  - University Hospitals Case Medical Center, Harrington Heart & Vascular Institute 
      Division of Cardiovascular Medicine.
FAU - Tam, M
AU  - Tam M
AD  - University Hospitals Case Medical Center, Harrington Heart & Vascular Institute 
      Division of Cardiovascular Medicine.
FAU - Parikh, S A
AU  - Parikh SA
AD  - University Hospitals Case Medical Center, Harrington Heart & Vascular Institute 
      Division of Cardiovascular Medicine.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20150210
PL  - England
TA  - Lupus
JT  - Lupus
JID - 9204265
SB  - IM
MH  - Adult
MH  - Antiphospholipid Syndrome/*complications
MH  - Cardiac Catheterization
MH  - Coronary Thrombosis/*complications
MH  - Electrocardiography
MH  - Humans
MH  - Laparotomy
MH  - Lupus Vasculitis, Central Nervous System/*complications/*diagnostic 
      imaging/surgery
MH  - Male
MH  - Myocardial Infarction/*etiology
MH  - Tomography, X-Ray Computed
OTO - NOTNLM
OT  - Cardiovascular disease
OT  - systemic lupus erythematosus
OT  - thrombosis
EDAT- 2015/02/13 06:00
MHDA- 2016/03/26 06:00
CRDT- 2015/02/13 06:00
PHST- 2014/11/17 00:00 [received]
PHST- 2015/01/07 00:00 [accepted]
PHST- 2015/02/13 06:00 [entrez]
PHST- 2015/02/13 06:00 [pubmed]
PHST- 2016/03/26 06:00 [medline]
AID - 0961203315570167 [pii]
AID - 10.1177/0961203315570167 [doi]
PST - ppublish
SO  - Lupus. 2015 Jul;24(8):885-8. doi: 10.1177/0961203315570167. Epub 2015 Feb 10.