PMID- 25672502 OWN - NLM STAT- MEDLINE DCOM- 20160412 LR - 20220310 IS - 1993-0402 (Electronic) IS - 1672-0415 (Linking) VI - 21 IP - 7 DP - 2015 Jul TI - Development and validation of a Lao Juan questionnaire. PG - 500-6 LID - 10.1007/s11655-015-2079-4 [doi] AB - OBJECTIVES: Lao Juan (LJ, ) is a syndrome described in Chinese medicine (CM) that manifests with fatigue, fever, spontaneous sweating, indigestion, work-induced pain, weakness of the limbs, and shortness of breath. The present study was conducted to examine the reliability and validity of a Lao Juan Questionnaire (LJQ). METHODS: A total of 151 outpatients and 73 normal subjects were asked to complete the LJQ. Seventy-three normal subjects were additionally asked to complete the Chalder Fatigue Scale (CFS). Twelve clinicians determined whether the 151 outpatients exhibited LJ or not. The internal consistency and construct validity for the LJQ were estimated using data from the outpatient subjects. The CFS data were used to examine the concurrent validity of the LJQ. Total LJQ scores and the clinicians᾿diagnoses of the outpatients were used to perform receiver operating characteristics (ROC) curve analyses and to define an optimum cut-off score for the LJQ. RESULTS: The 19-item LJQ had satisfactory internal consistency (alpha=0.828) and concurrent validity, with significant correlations between the LJQ and the CFS subscales. In the test of construct validity using principal component analysis, a total of six factors were extracted, and the overall variance explained by all factors was 59.5%. In ROC curve analyses, the sensitivity, specificity, and area under the curve were 76.0%, 59.2%, and 0.709, respectively. The optimum cut-off score was defined as six points. CONCLUSIONS: Our results suggest that the LJQ is a reliable and valid instrument for evaluating LJ. FAU - Yoon, Kyu-Jin AU - Yoon KJ AD - Department of Diagnosis and Biofunctional Medicine, College of Korean Medicine, Kyung Hee University, Seoul, Korea. FAU - Park, Young-Bae AU - Park YB FAU - Park, Young-Jae AU - Park YJ FAU - Kim, Min-Yong AU - Kim MY LA - eng PT - Journal Article DEP - 20150212 PL - China TA - Chin J Integr Med JT - Chinese journal of integrative medicine JID - 101181180 SB - IM MH - Adult MH - Fatigue/diagnosis MH - Female MH - Humans MH - Male MH - Pilot Projects MH - ROC Curve MH - Reproducibility of Results MH - Sensitivity and Specificity MH - *Surveys and Questionnaires MH - Young Adult EDAT- 2015/02/13 06:00 MHDA- 2016/04/14 06:00 CRDT- 2015/02/13 06:00 PHST- 2011/07/21 00:00 [received] PHST- 2015/02/13 06:00 [entrez] PHST- 2015/02/13 06:00 [pubmed] PHST- 2016/04/14 06:00 [medline] AID - 10.1007/s11655-015-2079-4 [doi] PST - ppublish SO - Chin J Integr Med. 2015 Jul;21(7):500-6. doi: 10.1007/s11655-015-2079-4. Epub 2015 Feb 12.